Results 11 to 20 of about 680,317 (306)

Treatment of multiple sclerosis in special populations: The case of refugees [PDF]

, 2020
Multiple sclerosis was long considered a relatively rare entity in the Middle East, but research over the past 10 years and the publication of the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis guidelines for multiple
Yamout, Bassem I., Zeineddine, Maya M.
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Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS [PDF]

, 2012
Despite significant progress in the development of therapies for relapsing MS, progressive MS remains comparatively disappointing. Our objective, in this paper, is to review the current challenges in developing therapies for progressive MS and identify ...
Salvetti, M, D. Brown, T. Coetzee, K. Sharrock, Lee, K, Brown, D, Feinstein, A, Thompson, A, K. Zuidwijk, D. Chandraratna, Kapoor, R, Fox, RJ, Zuidwijk, K, K. Lee, A. Thompson, G. Comi, Toosy, A, Baneke, P, Browne, P, Sharrock, K, O. Ciccarelli, P. Browne, A. Feinstein, Comi, G, R. J. Fox, Chandraratna, D, P. Zaratin, Baker, D, R. Kapoor, Ciccarelli, O, Zaratin, P, P. Baneke, Coetzee, T, D. Baker, SALVETTI, Marco, A. Toosy   +35 more
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Cerebrospinal fluid ATP metabolites in multiple sclerosis [PDF]

, 2010
Increased axonal energy demand and mitochondrial failure have been suggested as possible causes for axonal degeneration and disability in multiple sclerosis.Our objective was to test whether ATP depletion precedes clinical, imaging and biomarker evidence
Uitdehaag, BMJ, Di Pietro, V., Barkhof, F., Killestein, J, Belli, A.; id_orcid, Killestein, J., Uitdehaag, B.M.J., Eikelenboom, M.J., University of Catania, Tavazzi, B, Petzold, A.F.S., Petzold, A., Petzold, A, Belli, A., Eikelenboom, MJ, Lazzarino, G., Lazzarino, G, Di Pietro, V, Polman, CH, Amorini, A.M., Barkhof, F, Tavazzi, B., Polman, C.H., Belli, A, Di Pietro, V.; id_orcid, Amorini, AM, Pietro, V. Di   +26 more
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Multiple sclerosis associated with systemic sclerosis

Rheumatology International, 2006
Multiple sclerosis (MS) has been increasingly reported in association with other autoimmune diseases not primary affected the nervous system. The coexistence of MS and systemic sclerosis (SSc) has been rarely described. We report here the case of a 46-year-old female patient with longstanding MS since the age of 26, who developed SSc 12 years later ...
Pelidou, S. H., Tsifetaki, N., Giannopoulos, S., Deretzi, G., Voulgari, P., Kyritsis, A.   +5 more
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SUMMIT (Serially Unified Multicenter Multiple Sclerosis Investigation): creating a repository of deeply phenotyped contemporary multiple sclerosis cohorts. [PDF]

, 2018
BackgroundThere is a pressing need for robust longitudinal cohort studies in the modern treatment era of multiple sclerosis.ObjectiveBuild a multiple sclerosis (MS) cohort repository to capture the variability of disability accumulation, as well as ...
Uitdehaag, Bernard M.J., KAPPOS, L. D., Cree, Bruce Ac, Hauser, Stephen L., Chitnis, Tanuja, Cree, Bruce Anthony C.C., Montalban, Xavier, Bove, Riley, Weiner, Howard L, Hauser, Stephen L, Kappos, Ludwig, Khoury, Samia J., Khoury, Samia J, Weiner, Howard L., Tintoré, Mar, SUMMIT Consortium, Naegelin, Yvonne, Uitdehaag, Bernard Mj, Bové, Riley Marie   +18 more
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Challenges to Longitudinal Characterization of Lower Urinary Tract Dysfunction in Multiple Sclerosis [PDF]

, 2022
Background: Neurogenic lower urinary tract dysfunction (LUTD) results in lower urinary tract symptoms (LUTS) that impact quality of life in people with multiple sclerosis (PwMS).
Saraceno, Taylor J., Gopal, Arpita, Hauser, Stephen L., Polgar-Turcsanyi, Mariann, Chitnis, Tanuja, Cree, Bruce Anthony C.C., Kaplan, Tamara Bockow, Khoury, Samia J., Santaniello, Adam V., El-Ayoubi, Nabil K., Weiner, Howard L., Block, Valerie J., Gomez, Refujia, Consortium, Summit, Suskind, Anne M., Bové, Riley Marie, Zhao, Chao   +16 more
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Plasma Neurofilament Heavy Chain Levels Correlate to Markers of Late Stage Disease Progression and Treatment Response in SOD1(G93A) Mice that Model ALS [PDF]

, 2012
Background: Amyotrophic lateral sclerosis (ALS) is an incurable neurodegenerative disorder characterised by progressive degeneration of motor neurons leading to death, typically within 3–5 years of symptom onset. The diagnosis of ALS is largely reliant
Greensmith Linda, Dick, J., Lu, C.H., Malaspina, A., Kalmar, B., Greensmith, L., Dick, J, Petzold, A.F.S., Petzold, A, Linda Greensmith, Malaspina Andrea, Petzold Axel, Greensmith, L, Kalmar Bernadett, Kalmar, B, Dick James, Lu Ching-Hua, Lu, CH, Bernadett Kalmar, James Dick, Ching-Hua Lu, Lu, C-H, Andrea Malaspina, Malaspina, A, Axel Petzold   +24 more
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Toxocara infection in the differential diagnosis of multiple sclerosis in the Middle East [PDF]

, 2020
A critical step in the diagnosis of multiple sclerosis is to rule out a heterogeneous variety of multiple sclerosis mimickers, which is crucial in the era of powerful immune-modulator treatments.
El Najjar, Mayssam, El-Ayoubi, Nabil K., Atweh, Samir F., Baalbaki, Marwa M.   +3 more
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A grounded theory analysis of the occupational impact of caring for a partner who has multiple sclerosis [PDF]

, 2006
Chronic progressive conditions such as multiple sclerosis impact engagement in and orchestration of daily occupations by people with the condition, and their family members.
Molineaux, M, Molineux, Matthew, Heward, Kate, Heward, K, Gough, B, Gough, B., Gough, Brendan, Heward, K.   +7 more
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External validation of a clinical prediction model in multiple sclerosis [PDF]

, 2023
Background: Timely initiation of disease modifying therapy is crucial for managing multiple sclerosis (MS). Objective: We aimed to validate a previously published predictive model of individual treatment response using a non-overlapping cohort from the ...
Inshasi, Jihad, Malpas, Charles B, Yamout, Bassem I., Altıntaş, Ayşe, Yamout, Bassem, Türkoǧlu, Recai, Sharmin, Sifat, Shalaby, Nevin Mohieldin, Karabudak, Rana, Al-Harbi, Talal, Shalaby, Nevin, Shaygannejad, Vahid, Khoury, Samia J., Khoury, Samia J, Boz, Cavit, Soysal, Aysun, Alroughani, Raed, Inshasi, Jihad Said, Terzi, Murat, Moradi, Nahid, Malpas, Charles B., Alroughani, Raed A., Al-Harbi, Talal M., Kalincik, Tomas, Altintaş, Ayşe   +24 more
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