Results 31 to 40 of about 680,317 (306)

Combining tractography and cortical measures to test system-specific hypotheses in multiple sclerosis. [PDF]

, 2010
The objective was to test three motor system-specific hypotheses in multiple sclerosis patients: (i) corticospinal tract and primary motor cortex imaging measures differ between multiple sclerosis patients and controls; (ii) in patients, these measures ...
Ciccarelli, Olga, Thompson, Alan J, Gorgoraptis, Nikos, Wheeler-Kingshott, Claudia AM, Altmann, Daniel R, Jenkins, Thomas M, Miller, David H   +6 more
core   +1 more source

Central Nervous System Tumors Among Infants in Canada: A Report From CYP‐C

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) tumors in infants are rare, pose unique clinical challenges, and lack large‐scale evidence‐based data to guide management. This study seeks to describe CNS tumors in Canadian infants and to compare their outcomes with those of older children.
Samuel Sassine, Hallie Coltin, Sylvia Cheng, Lucie Lafay‐Cousin, Vanan Issai Magimairajan, Craig Erker, Stéphanie Vairy, Lynette Bowes, Adam Fleming, Donna Johnston, Sarah McKillop, Roona Sinha, Julie Bennett, Christina Coleman, Laura Wheaton, Shayna Zelcer, Samuele Renzi, Thai Hoa Tran   +17 more
wiley   +1 more source

Radiologically isolated syndrome and multiple sclerosis [PDF]

, 2017
Background Incidental white matter lesions (WML) are increasingly seen on brain magnetic resonance imaging (MRI) in clinical practice. Demyelination consistent with MS is seen in 0.1–0.7% of the population as evident by autopsy and MRI studies.
AlKhawajah, Mona Marwan, B. Yamout, M. Al Khawajah, Yamout, Bassem I.   +3 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Multiplex cytokine analysis of dermal interstitial blister fluid defines local disease mechanisms in systemic sclerosis. [PDF]

, 2015
Clinical diversity in systemic sclerosis (SSc) reflects multifaceted pathogenesis and the effect of key growth factors or cytokines operating within a disease-specific microenvironment.
Christopher P Denton, Lopez, H, Etomi, O, Korsa Khan, George R Martin, Abraham, DJ, Guerra, SG, Denton, CP, Sandra G Guerra, Xu Shiwen, David J Abraham, Bahja Ahmed Abdi, Richard J Stratton, Kristina EN Clark, Oseme Etomi, Shiwen, X, Henry Lopez, Abdi, BA, Martin, GR, Stratton, RJ, Khan, K, Clark, KE   +21 more
core   +1 more source

Consensus recommendations for the diagnosis and treatment of multiple sclerosis: 2019 revisions to the MENACTRIMS guidelines [PDF]

, 2020
With evolving diagnostic criteria and the advent of new oral and parenteral therapies for MS, most current diagnostic and treatment algorithms need revision and updating.
Almahdawi, Akram M., Dahdaleh, Maurice P., Alsaadi, Taoufik M., Inshasi, Jihad Said, Yamout, Bassem I., Bohlega, Saeed A., Al-Jumah, Mohammed A., Alsharoqi, Isa Ahmed, Koussa, Salam F., AlKhawajah, Mona Marwan, Al Khaburi, J., Alroughani, Raed A., Goueider, Riyad, Khoury, Samia J., Sahraian, Mohammad Ali, Daodi, S., Slassi, E., Zakaria, Magd Fouad, Hashem, Saher S.   +18 more
core   +1 more source

Mesial Temporal Lobe Epilepsy as a Common but Elusive Case: A Case Report

Qanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya
Epilepsy is a common neuronal disorder that could include partial or generalized seizures due to abnormal brain electrical activity. A 32-year-old female patient was presented to the emergency room with a chief complaint of seizure.
Darren Junior, Putu Kintan Wulandari, Saktivi Harkitasari, I Wayan Sumardika, Komang Trisna Sumadewi   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Some features of sclerotic processes in the walls of the bile ducts and gall bladder in chronic bile tract diseases (a review of literature)

Известия высших учебных заведений. Поволжский регион: Медицинские науки, 2022
The article presents the results of studies of variants of the development of sclerotic changes in the liver tissue, intrahepatic and extrahepatic ducts, as well as the walls of the gallbladder associated with various chronic diseases of the biliary ...
M.G. Fedorova, E.V. Komarova, N.O. Tsyplikhin   +2 more
doaj   +1 more source

Surgical resection of symptomatic calcinosis in a patient with systemic sclerosis [PDF]

Revista Brasileira de Cirurgia Plástica, 2019
Introduction: Systemic sclerosis is a rare, autoimmune, progressive disease that affects connective tissues and internal organs by inflammation, which can cause calcinosis cutis.
Caio Pundek Garcia, Natalia Biancha Rendon, Carlo Mognon Mattiello, Flávia Cristina de Novaes Gerber, Jorge Bins-Ely   +4 more
doaj   +1 more source