Multiple sclerosis (MS) is a chronic, complex neurological disease with a variable clinical course in which several pathophysiological mechanisms such as axonal/ neuronal damage, demyelination, inflammation, gliosis, remyelination and repair, oxidative injury and excitotoxicity, alteration of the immune system as well as biochemical disturbances and ...
Alyssa, Nylander, David A, Hafler
openaire +4 more sources
Primary Sclerosing Lipogranuloma: A Rare Cause of Scrotal Mass [PDF]
Sclerosing Lipogranuloma (SLG) is a rare disease that affects many organs, with male genitourinary system being the most common site. It is a benign disease which occurs due to a granulomatous reaction of fatty tissue in this area.
Smita Singh +3 more
doaj +1 more source
Using normalisation process theory to understand barriers and facilitators to implementing mindfulness-based stress reduction for people with multiple sclerosis [PDF]
Objectives: To study barriers and facilitators to implementation of mindfulness-based stress reduction for people with multiple sclerosis. Methods: Qualitative interviews were used to explore barriers and facilitators to implementation of ...
Mair, Frances S. +4 more
core +1 more source
Melorheostosis in a 12-year-old child
Melorheostosis (of Leriand Joanny) is a rare, non-genetic sclerotic dysplatic bone disorder presenting at any age, usually from late childhood to adulthood. Its aetiology is unknown. It affects mainly the long bones of the upper and lower limbs, but also
S. Andronikou, B. Smith
doaj +1 more source
Vitamin D and Disease Severity in Multiple Sclerosis-Baseline Data From the Randomized Controlled Trial (EVIDIMS) [PDF]
Objective: To investigate the associations between hypovitaminosis D and disease activity in a cohort of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS) patients.
Bellmann-Strobl, Judith +7 more
core +2 more sources
A rare case of tumoral scleromyxedema
Scleromyxedema is an uncommon disease, affecting the skin mainly and other internal organs sometimes, characterized by fibroblasts proliferation, fibrosis, and mucous deposition in the absence of thyroid disorder.
Ali Sadeghinia +5 more
doaj +1 more source
The clinical- and cost-effectiveness of functional electrical stimulation and ankle-foot orthoses for foot drop in Multiple Sclerosis: a multicentre randomized trial [PDF]
Objective: To compare the clinical- and cost-effectiveness of ankle-foot orthoses (AFOs) and functional electrical stimulation (FES) over 12 months in people with Multiple Sclerosis with foot drop.
Bowers, Roy +7 more
core +2 more sources
Botulinum toxin for the treatment of lower limb cramp pain in patients with Amyotrophic Lateral Sclerosis [PDF]
Background: Muscle cramps and pain associated with them can be seen in patients with amyotrophic lateral sclerosis (ALS) and are known to reduce the quality of life. Pharmacological treatment may not benefit all patients in treating these cramps.
Govindarajan, Raghav +2 more
core +2 more sources
Mesial temporal sclerosis in children Esclerose mesial temporal em crianças
Mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children.
Eliana Maria Domingues Brandão +1 more
doaj +1 more source
A Case Report of Systemic Sclerosis Complicated by Biventricular Heart Failure, Pulmonary Hypertension and Review of Literature [PDF]
Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disorder whose aetiology is not fully understood. Skin fibrosis and visceral organs involvement are the hallmarks, and the heart could be disproportionately or subtly involved ...
Akinboro AO +3 more
core +1 more source

