Results 41 to 50 of about 30,257 (118)
Intranasal scopolamine preparation and method [PDF]
A new method and preparation for intranasal delivery of scopolamine provides a safe and effective treatment for motion sickness and other conditions requiring anticholinergic therapy. The preparation can be in the form of aqueous nasal drops, mist spray,
Cintron, Nitza M., Putcha, Lakshmi
core +1 more source
Overnight transdermal scopolamine patch administration has no clear effect on cognition and emotional processing in healthy volunteers [PDF]
There has been increasing interest in the antidepressant effects of the muscarinic cholinergic receptor antagonist scopolamine. Here we assess, for the first time, whether a transdermal scopolamine patch is sufficient to induce changes in cognition that ...
Browning, Michael+4 more
core +2 more sources
Acute enhancement of cardiac vagal efficiency (VE) is demonstrated with active compared to sham percutaneous electrical nerve field stimulation (PENFS). This effect is not found in children chronically exposed to antidepressants with anticholinergic and serotonergic effects. Figure created in BioRender.com.
Jacek Kolacz+3 more
wiley +1 more source
Our research is the first to explore the neuroprotective effects of total saponin active compounds isolated from Panax quinquefolius after steaming different times, and to screen out those total saponins with better neuroprotective activity, as well as to conduct a preliminary study on their potential to improve learning and memory impairments. Results
Yuting Yang+7 more
wiley +1 more source
The muscarinic antagonists scopolamine and atropine are competitive antagonists at 5-HT3 receptors. [PDF]
Scopolamine is a high affinity muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. 5-HT3 receptor antagonists are used for the same purpose and are structurally related to scopolamine.
Lochner, Martin, Thompson, Andrew J
core +3 more sources
Abstract An 11‐year‐old, female West Highland white terrier presenting cough, emesis, diarrhoea and hyporexia refractory to symptomatic treatment was subjected to endoscopy showing increased palatine tonsil region. Biopsy findings revealed a carcinoma. Computed tomography also showed an increased right medial retropharyngeal lymph node dorsally related
Jiuli R. S. de Salles+2 more
wiley +1 more source
The brattleboro rat displays a natural deficit in social discrimination that is restored by clozapine and a neurotensin analog. [PDF]
Cognitive deficits in schizophrenia are a major source of dysfunction for which more effective treatments are needed. The vasopressin-deficient Brattleboro (BRAT) rat has been shown to have several natural schizophrenia-like deficits, including ...
Feifel, D+5 more
core +2 more sources
Abstract Aim The aim of this study was to investigate the impact of pharmacist‐led person‐centred medicines reviews in general practices on medicines appropriateness, polypharmacy indicators (high‐risk prescribing markers), and patient‐reported outcome measures (PROMs).
Clare Kinahan+9 more
wiley +1 more source
Neurophysiological responses to stressful motion and anti-motion sickness drugs as mediated by the limbic system [PDF]
Performance is characterized in terms of attention and memory, categorizing extrinsic mechanism mediated by ACTH, norepinephrine and dopamine, and intrinsic mechanisms as cholinergic.
Kohl, R. L., Odell, S.
core +1 more source
Ameliorating the effect of Zingiber officinale (ginger) hydroethanolic extract on scopolamine-induced memory impairment in adult male rats [PDF]
Background and aims: The spice Zingiber officinale or ginger possesses antioxidant and neuroprotective effects. In this study we hypothesized that treatment with hydroethanolic extract of ginger (50, 100 and 200 mg/kg, p.o) would have an effect on the ...
Gomar, A.+3 more
core