Results 31 to 40 of about 17,592 (189)

Effect of Glycyrrhizic Acid on Scopolamine-Induced Cognitive Impairment in Mice [PDF]

open access: yesInternational Neurourology Journal, 2020
Purpose Cognitive impairment is one of the main symptoms of Alzheimer disease and other dementias. Glycyrrhiza uralensis is a natural product that has a protective effect against cognitive impairment.
Ju Yeon Ban   +2 more
doaj   +1 more source

Natural selection drives chemical resistance of Datura stramonium [PDF]

open access: yesPeerJ, 2016
Plant resistance to herbivores involves physical and chemical plant traits that prevent or diminish damage by herbivores, and hence may promote coevolutionary arm-races between interacting species.
Adán Miranda-Pérez   +9 more
doaj   +2 more sources

Perioperative Intravenous Dexamethasone Improves Pain and Functional Outcomes After Arthroscopic Rotator Cuff Repair

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate the effect of perioperative dexamethasone on patient‐reported pain, functional outcomes, and minimal clinically important difference (MCID) achievement following arthroscopic rotator cuff repair. Methods Patients who underwent rotator cuff repair between 2013 and 2023 were identified and divided into groups.
Trevor D. Wolterink   +9 more
wiley   +1 more source

Improvement of cognitive deficit of curcumin on scopolamine-induced Alzheimer’s disease models

open access: yesCaspian Journal of Internal Medicine, 2022
Background: It has been suggested that curcumin may be useful in diseases with cognitive dysfunction because it slows the progression and leads to the improvement of cognitive functions.
Guzin Cakmak   +5 more
doaj  

Targeted senotherapy improves electrographic and behavioral outcomes in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Current pharmacotherapy for temporal lobe epilepsy (TLE) is limited to symptomatic treatment and leaves approximately one third of patients with inadequate seizure control. Discovering disease‐modifying targets is an unmet clinical need. We have previously identified senescent cells (SCs) as one such target. Many drugs that eliminate
David J. McFall   +3 more
wiley   +1 more source

Black seed oil ameliorated scopolamine-induced memory dysfunction and cortico-hippocampal neural alterations in male Wistar rats

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2016
This study was conducted to evaluate cognitive enhancing effect and ameliorative effects of black seed oil in scopolamine induced rat model of cognitive impairment.
A. Imam   +10 more
doaj   +1 more source

A consensus roadmap for post‐traumatic epilepsy: Clinical biomarkers, research priorities, policy barriers, and pathways to interventional trials

open access: yesEpilepsia, EarlyView.
Abstract Understanding the mechanisms underlying post‐traumatic epilepsy (PTE) following traumatic brain injury (TBI), and developing strategies to prevent or modify its progression, has been the focus of large collaborative efforts within the epilepsy and TBI research communities for over a decade.
Elisa R. Zanier   +82 more
wiley   +1 more source

Biofluid‐specific variations in circulating 5′ transfer RNA fragments during ictal and interictal states in experimental temporal lobe epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Circulating small noncoding RNAs represent potential biomarkers of temporal lobe epilepsy (TLE). Recently, two transfer RNA fragments (tRFs), 5′tRF Glu‐CTC and Gly‐GCC, were found to be elevated in plasma samples collected in advance of a seizure in TLE patients, suggesting they may serve as potential wet biomarkers of seizure risk ...
Marie Soukupova   +15 more
wiley   +1 more source

Different effects of scopolamine on learning, memory, and nitric oxide metabolite levels in hippocampal tissues of ovariectomized and Sham-operated rats

open access: yesArquivos de Neuro-Psiquiatria, 2012
Different effects of scopolamine on learning, memory, and nitric oxide (NO) metabolites in hippocampal tissues of ovariectomized (OVX) and sham-operated rats were investigated.
Hamid Azizi-Malekabadi   +5 more
doaj   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

open access: yesEpilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson   +2 more
wiley   +1 more source

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