Results 11 to 20 of about 34,687 (233)

Effect of scopolamine-based amnesia on the number of astrocytes in the rat's hippocampus [PDF]

open access: yes, 2012
As neuron-astrocyte interactions play a crucial role in the adult brain, it is thought that astrocytes support learning and memory through specific mechanisms.
Azami, N.S.   +2 more
core   +1 more source

Protection against brain tissues oxidative damage as a possible mechanism for improving effects of low doses of estradiol on scopolamine-induced learning and memory impairments in ovariectomized rats

open access: yesAdvanced Biomedical Research, 2016
Background: Regarding the anti-oxidative effects on the central nervous system, the possible protection against brain tissues oxidative damage as a possible mechanism for improving effects of low doses of estradiol on scopolamine-induced learning and ...
Seyed Hassan Hejazian   +4 more
doaj   +1 more source

Inhibition of Connexin43 hemichannels impairs spatial short-term memory without affecting spatial working memory [PDF]

open access: yes, 2016
Astrocytes are active players in higher brain function as they can release gliotransmitters, which are essential for synaptic plasticity. Various mechanisms have been proposed for gliotransmission, including vesicular mechanisms as well as non-vesicular ...
Albertini, Giulia   +5 more
core   +2 more sources

Surfactant protein D contributes to ocular defense against Pseudomonas aeruginosa in a murine model of dry eye disease. [PDF]

open access: yes, 2013
Dry eye disease can cause ocular surface inflammation that disrupts the corneal epithelial barrier. While dry eye patients are known to have an increased risk of corneal infection, it is not known whether there is a direct causal relationship between ...
Evans, David   +4 more
core   +7 more sources

Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors

open access: yesNeurobiology of Disease, 2015
Clinical studies demonstrate that scopolamine, a non-selective muscarinic acetylcholine receptor (mAchR) antagonist, produces rapid therapeutic effects in depressed patients, and preclinical studies report that the actions of scopolamine require ...
Andrea Navarria   +10 more
doaj   +1 more source

The influence of scopolamine on motor control and attentional processes [PDF]

open access: yesPeerJ, 2016
Background: Motion sickness may be caused by a sensory conflict between the visual and the vestibular systems. Scopolamine, known to be the most effective therapy to control the vegetative symptoms of motion sickness, acts on the vestibular nucleus and ...
Emma Bestaven   +4 more
doaj   +2 more sources

Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]

open access: yes, 2016
Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark   +5 more
core   +1 more source

Scopolamine administration modulates muscarinic, nicotinic and NMDA receptor systems.

open access: yesPLoS ONE, 2012
Studies on the effect of scopolamine on memory are abundant but so far only regulation of the muscarinic receptor (M1) has been reported. We hypothesized that levels of other cholinergic brain receptors as the nicotinic receptors and the N-methyl-D ...
Soheil Keihan Falsafi   +4 more
doaj   +1 more source

Effect of Nigella sativa and wheat germ oils on scopolamine-induced memory impairment in rats

open access: yesBulletin of Faculty of Pharmacy Cairo University, 2012
Aim: To investigate the possible memory enhancing effects of Nigella sativa oil (NSO) and wheat germ oil (WGO) on scopolamine-induced amnesic rats. Methods: Male Wistar rats received either saline or scopolamine (16 mg/kg, i.p.).
Salma A. El-Marasy   +4 more
doaj   +1 more source

Effects of Matricaria chamomilla extract on motor coordination impairment induced by scopolamine in rats

open access: yesAsian Pacific Journal of Tropical Biomedicine, 2015
Objective: To evaluate the effect of ethanolic extract of chamomile on balance and motor learning in rats receiving scopolamine and intact rats. Methods: Fourty-two rats were divided into 6 groups (n = 7). Control group received distilled water.
Samira Asgharzade   +2 more
doaj   +1 more source

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