The influence of scopolamine on motor control and attentional processes [PDF]
PeerJ, 2016 Background: Motion sickness may be caused by a sensory conflict between the visual and the vestibular systems. Scopolamine, known to be the most effective therapy to control the vegetative symptoms of motion sickness, acts on the vestibular nucleus and ...
Emma Bestaven +4 more
doaj +3 more sources
Scopolamine administration modulates muscarinic, nicotinic and NMDA receptor systems.
PLoS ONE, 2012 Studies on the effect of scopolamine on memory are abundant but so far only regulation of the muscarinic receptor (M1) has been reported. We hypothesized that levels of other cholinergic brain receptors as the nicotinic receptors and the N-methyl-D ...
Soheil Keihan Falsafi +4 more
doaj +2 more sources
Application of Metabolic Engineering to the Production of Scopolamine [PDF]
Molecules, 2008 Scopolamine is an alkaloid widely used in medicine for its anticholinergic activity. The aim of this review is to show that metabolic engineering techniques constitute a suitable tool to improve the production of tropane alkaloids, focusing in particular
Mohammad Hossein Mirjalili +3 more
doaj +2 more sources
Effects of scopolamine on matching to sample paradigm and related tests in human subjects [PDF]
, 2003 This was a double-blind placebo-controlled study with a cross-over design to examine the effects of scopolamine on cognitive functions in young healthy subjects.
Engel, R. +6 more
core +1 more source
Infusions of scopolamine in dorsal hippocampus reduce anticipatory responding in an appetitive trace conditioning procedure [PDF]
, 2018 Trace conditioning is impaired by lesions to dorsal hippocampus, as well as by treatment with the muscarinic acetylcholine antagonist scopolamine. However, the role of muscarinic receptors within hippocampus has received little attention.
Hayley J. Marshall +5 more
core +1 more source
Differing time dependencies of object recognition memory impairments produced by nicotinic and muscarinic cholinergic antagonism in perirhinal cortex [PDF]
, 2011 The roles of muscarinic and nicotinic cholinergic receptors in perirhinal cortex in object recognition memory were compared. Rats' discrimination of a novel object preference test (NOP) test was measured after either systemic or local infusion into the ...
Warburton, E Clea +20 more
core +1 more source
Critical role of the cholinergic system for object-in-place associative recognition memory [PDF]
, 2009 Object-in-place memory, which relies on the formation of associations between an object and the place in which it was encountered, depends upon a neural circuit comprising the perirhinal (PRH) and medial prefrontal (mPFC) cortices.
Warburton, Elizabeth C, Barker, GRI
core +1 more source
Supra and subgingival application of antiseptics or antibiotics during periodontal therapy
Periodontology 2000, EarlyView., 2023 Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero +5 more
wiley +1 more source
Neurobiology of Disease, 2015 Clinical studies demonstrate that scopolamine, a non-selective muscarinic acetylcholine receptor (mAchR) antagonist, produces rapid therapeutic effects in depressed patients, and preclinical studies report that the actions of scopolamine require ...
Andrea Navarria +10 more
doaj +1 more source