Results 131 to 140 of about 291,183 (179)

Indole-Based Compounds in the Development of Anti-Neurodegenerative Agents. [PDF]

Molecules
Barresi E, Baglini E, Poggetti V, Castagnoli J, Giorgini D, Salerno S, Taliani S, Da Settimo F.   +7 more
europepmc   +1 more source

Effects of New Galantamine Derivatives in a Scopolamine Model of Dementia in Mice

Journal of Alzheimer's Disease, 2021
Alzheimer’s disease (AD), a progressive neurodegenerative disorder characterized by memory loss and cognitive functions decline, is a leading cause for dementia and currently ranked as the sixth foremost cause of death. As of present, treatment of AD is symptomatic without convincing therapeutic benefits and new, effective, therapeutic agents are ...
Maria Lazarova, Lyubka Tancheva, Albena Alexandrova, Elina Tsvetanova, Almira Georgieva, M. Stefanova, Daniela S. Tsekova, L. Vezenkov, Reni Kalfin, Diamara Uzunova, Polina Petkova‐Kirova   +10 more
openalex   +4 more sources

Validated capillary electrophoresis method for the determination of atropine and scopolamine derivatives in pharmaceutical formulations

Journal of Pharmaceutical and Biomedical Analysis, 1998
The simultaneous determination of atropine and scopolamine derivatives, which have similar structures, was investigated by using capillary zone electrophoresis. The effects of buffer pH, buffer concentration and hydroxypropyl-beta-cyclodextrin concentration on migration time and resolution of the investigated compounds were systematically studied.
Samir Cherkaoui, Lidia Mateus, Philippe Christen, Jean‐Luc Veuthey   +3 more
openalex   +5 more sources

The Kinetics of Hydrolysis of Scopolamine Derivatives with an Unusual Elimination on Alkaline Hydrolysis¹

Journal of the American Chemical Society, 1957
Edward R. Garrett
openalex   +3 more sources

Colorimetric Determination of Atropine, Homatropine, Scopolamine, and Their Derivatives by the Ferric Hydroxamate Method

Journal of Pharmaceutical Sciences, 1970
The purpose of this study was to develop a procedure for the quantitative analysis of the salts of the solanaceous alkaloids in the presence of their hydrolysis products. The salts taken were atropine sulfate, homatropine hydrobromide, homatropine methyl-bromide, scopolamine hydrobromide, and scopolamine methyl-bromide. The ferric hydroxamate procedure
Joseph A. Feldman, Bruce J. Robb
openalex   +4 more sources

Antispasmodics. VIII. Scopolamine Derivatives

Journal of the American Chemical Society, 1956
Robert Bruce Moffett, Brooke D. Aspergren   +1 more
openalex   +3 more sources

Water-soluble derivative of propolis mitigates scopolamine-induced learning and memory impairment in mice

Pharmacology Biochemistry and Behavior, 2008
The water-soluble derivative of propolis (WSDP) was prepared from fresh Chinese propolis. Its major constituents were identified by high performance liquid chromatography (HPLC) analysis. It has been reported that propolis possessed a broad spectrum of biological activities but including few studies on learning and memory by now.
Juan Chen, Yuan Long, Min Su Han, Ting Wang, Qiang Chen, Rui Wang   +5 more
openalex   +4 more sources

Ameliorative effects of amide derivatives of 1,3,4-thiadiazoles on scopolamine induced cognitive dysfunction

European Journal of Medicinal Chemistry, 2016
The present study reports the effect of amide derivatives of 1,3,4-thiadizoles on scopolamine induced deficit cholinergic neurotransmission and oxidative stress serving as promising leads for the therapeutics of cognitive dysfunction. Fourteen compounds (2c-8d) have been synthesised and evaluated against behavioural alterations using step down passive ...
Akanksha Kulshreshtha, Poonam Piplani
openalex   +4 more sources

Ameliorative effects of 1,3,4-thiadiazole derivatives on scopolamine induced cognitive deficits in mice

Parkinsonism & Related Disorders, 2015
Akanksha Kulshreshtha, Poonam Piplani
  +5 more sources