Results 151 to 160 of about 3,294 (199)

Pharmacological Evaluation of Tropane Analogues at the Serotonin Transporter. [PDF]

ACS Chem Neurosci
Avanes AA, Warren HT, Senthil A, Olson DE.   +3 more
europepmc   +1 more source

Neuroprotective effects of traditional Chinese medicine using zebrafish models - a review. [PDF]

Front Pharmacol
Shao J, An Y, Ding R, Wang S, Wang X.
europepmc   +1 more source

Comprehensive medicinal chemistry survey highlights a portfolio of lead molecules for Alzheimer's disease therapy. [PDF]

Front Chem
Bhansali PR, Sonkusare SM, Savale SS, Wijayasinghe YS, Liao Y, Sloan DC, Chaturbhuj GU, Muntean BS.   +7 more
europepmc   +1 more source

Marine-Derived Natural Substances with Anticholinesterase Activity. [PDF]

Mar Drugs
Dimitrova D, Kehayova G, Dimitrova S, Dragomanova S.   +3 more
europepmc   +1 more source

Neuroprotective effects of essential oils in animal models of Alzheimer's and Parkinson's disease: a systematic review. [PDF]

PeerJ
Macedo ADES, Ferreira TM, Krejcová LV, Rocha FAF, da Silva JKR, Pedrosa LRR, Gomes BD.   +6 more
europepmc   +1 more source

Validated capillary electrophoresis method for the determination of atropine and scopolamine derivatives in pharmaceutical formulations

Journal of Pharmaceutical and Biomedical Analysis, 1998
The simultaneous determination of atropine and scopolamine derivatives, which have similar structures, was investigated by using capillary zone electrophoresis. The effects of buffer pH, buffer concentration and hydroxypropyl-beta-cyclodextrin concentration on migration time and resolution of the investigated compounds were systematically studied.
Samir Cherkaoui, Philippe Christen, Jean-Luc Veuthey   +2 more
exaly   +6 more sources

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Colorimetric Determination of Atropine, Homatropine, Scopolamine, and Their Derivatives by the Ferric Hydroxamate Method

Journal of Pharmaceutical Sciences, 1970
The purpose of this study was to develop a procedure for the quantitative analysis of the salts of the solanaceous alkaloids in the presence of their hydrolysis products. The salts taken were atropine sulfate, homatropine hydrobromide, homatropine methyl-bromide, scopolamine hydrobromide, and scopolamine methyl-bromide. The ferric hydroxamate procedure
J A, Feldman, B J, Robb
exaly   +3 more sources

Ameliorative effects of amide derivatives of 1,3,4-thiadiazoles on scopolamine induced cognitive dysfunction

European Journal of Medicinal Chemistry, 2016
The present study reports the effect of amide derivatives of 1,3,4-thiadizoles on scopolamine induced deficit cholinergic neurotransmission and oxidative stress serving as promising leads for the therapeutics of cognitive dysfunction. Fourteen compounds (2c-8d) have been synthesised and evaluated against behavioural alterations using step down passive ...
Akanksha Kulshreshtha, Poonam Piplani
exaly   +3 more sources

Scopolamine Derivatives as Potential Pharmaceuticals with Calixarene-CyclodextrineNanosponges as Drug Carriers [PDF]

, 2017
Tropane alkaloids are molecules with a strong biological activity, which are mainly produced by the members offamily Solanaceae, but also found inother plant families (Convolvulaceae, Brasicaceae, Erythroxylaceae andEuphorbiaceae).1 More than 20 active pharmaceutical substances containingthetropane moiety have been industrially produced and applied as ...
G. Rizzo, G. Catinella, S. Rosselli, P. Lo Meo, M. Bruno   +4 more
openaire   +1 more source

Neuroprotective effects of novel pyrrolidine-2-one derivatives on scopolamine-induced cognitive impairment in mice: Behavioral and biochemical analysis

Pharmacology Biochemistry and Behavior, 2023
Alzheimer's disease (AD) is a long-term neurodegenerative condition that impairs cognitive abilities. In brain acetylcholine deficit and oxidative stress may be considered the key pathogenic causes for AD, even though the basic etiology is still unknown.
Swati Pant, Monika Chauhan, Sumitra Nain   +2 more
exaly   +3 more sources