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Antispasmodics. VIII. Scopolamine Derivatives

Journal of the American Chemical Society, 1956
Robert Bruce Moffett
exaly   +2 more sources

Effects of New Galantamine Derivatives in a Scopolamine Model of Dementia in Mice

Journal of Alzheimer's Disease, 2021
Alzheimer’s disease (AD), a progressive neurodegenerative disorder characterized by memory loss and cognitive functions decline, is a leading cause for dementia and currently ranked as the sixth foremost cause of death. As of present, treatment of AD is symptomatic without convincing therapeutic benefits and new, effective, therapeutic agents are ...
Maria, Lazarova   +10 more
openaire   +2 more sources

Validated capillary electrophoresis method for the determination of atropine and scopolamine derivatives in pharmaceutical formulations

Journal of Pharmaceutical and Biomedical Analysis, 1998
The simultaneous determination of atropine and scopolamine derivatives, which have similar structures, was investigated by using capillary zone electrophoresis. The effects of buffer pH, buffer concentration and hydroxypropyl-beta-cyclodextrin concentration on migration time and resolution of the investigated compounds were systematically studied.
Jean-Luc Veuthey   +2 more
exaly   +5 more sources

Ameliorative effects of amide derivatives of 1,3,4-thiadiazoles on scopolamine induced cognitive dysfunction

European Journal of Medicinal Chemistry, 2016
The present study reports the effect of amide derivatives of 1,3,4-thiadizoles on scopolamine induced deficit cholinergic neurotransmission and oxidative stress serving as promising leads for the therapeutics of cognitive dysfunction. Fourteen compounds (2c-8d) have been synthesised and evaluated against behavioural alterations using step down passive ...
Poonam Piplani, Akanksha Kulshreshtha
exaly   +3 more sources

Colorimetric Determination of Atropine, Homatropine, Scopolamine, and Their Derivatives by the Ferric Hydroxamate Method

Journal of Pharmaceutical Sciences, 1970
The purpose of this study was to develop a procedure for the quantitative analysis of the salts of the solanaceous alkaloids in the presence of their hydrolysis products. The salts taken were atropine sulfate, homatropine hydrobromide, homatropine methyl-bromide, scopolamine hydrobromide, and scopolamine methyl-bromide. The ferric hydroxamate procedure
J A, Feldman, B J, Robb
exaly   +3 more sources

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