Results 1 to 10 of about 431 (130)

Scopoletin: a review of its pharmacology, pharmacokinetics, and toxicity

Frontiers in Pharmacology
Scopoletin is a coumarin synthesized by diverse medicinal and edible plants, which plays a vital role as a therapeutic and chemopreventive agent in the treatment of a variety of diseases. In this review, an overview of the pharmacology, pharmacokinetics,
Xiaoyan Gao
exaly   +5 more sources

Advances in biosynthesis of scopoletin

Microbial Cell Factories, 2022
Scopoletin is a typical example of coumarins, which can be produced in plants. Scopoletin acts as a precursor for pharmaceutical and health care products, and also possesses promising biological properties, including antibacterial, anti-tubercular, anti ...
Bo-Tao He, Zhi-Hua Liu, Bing-Zhi Li, Ying-Jin Yuan   +3 more
doaj   +3 more sources

Pharmacogenomics of Scopoletin in Tumor Cells [PDF]

Molecules, 2016
Drug resistance and the severe side effects of chemotherapy necessitate the development of novel anticancer drugs. Natural products are a valuable source for drug development.
Ean-Jeong Seo, Mohamed Saeed, Betty Yuen Kwan Law, An Guo Wu, Onat Kadioglu, Henry Johannes Greten, Thomas Efferth   +6 more
doaj   +3 more sources

Acaricidal Mechanism of Scopoletin Against Tetranychus cinnabarinus [PDF]

Frontiers in Physiology, 2019
Scopoletin is a promising acaricidal botanical natural compound against Tetranychus cinnabarinus, and its acaricidal mechanism maybe involve calcium overload according to our previous study.
Hong Zhou, Yong-qiang Zhang, Ting Lai, Xue-jiao Liu, Fu-you Guo, Tao Guo, Wei Ding   +6 more
doaj   +3 more sources

Scopoletin Induced Metabolomic Profile Disturbances in Zebrafish Embryos

Metabolites, 2022
Scopoletin, a typical example of a coumarin compound, exists in several Artemisia species and other plant genera. However, the systemic metabolic effects induced by scopoletin remain unclear.
Weixuan Yao, Jingpei Chen, Zhanyu Lin, Nani Wang, Anli Wang, Binjie Wang, Yuanzhao Wu, Zhongshi Xu, Jiye Wang   +8 more
doaj   +1 more source

Scopoletin

Asian Pacific Journal of Tropical Biomedicine, 2023
Cancer is considered a leading cause of death worldwide due to its high morbidity and mortality rate. Conventional treatments for cancer therapy, such as chemotherapy, and radiotherapy, have been hampered by their side effects. Natural product-derived plants have been used for decades to treat diseases.
Lia Meilawati, Rita Marleta Dewi, Aprilia Nur Tasfiyati, Abdi Wira Septama, Lucia Dwi Antika   +4 more
openaire   +2 more sources

Hydroxycoumarin Scopoletin Inhibits Bone Loss through Enhancing Induction of Bone Turnover Markers in a Mouse Model of Type 2 Diabetes

Biomedicines, 2021
Diabetes induces bone deterioration, which leads to increased risk of fracture, osteopenia, and osteoporosis. Thus, diabetes-associated bone fragility has been recognized as a diabetic complication.
Eun-Jung Lee, Woojin Na, Min-Kyung Kang, Yun-Ho Kim, Dong-Yeon Kim, Hyeongjoo Oh, Soo-Il Kim, Su-Yeon Oh, Sohyun Park, Kyungho Park, Young-Hee Kang   +10 more
doaj   +1 more source

Antifungal Activity of the Natural Coumarin Scopoletin Against Planktonic Cells and Biofilms From a Multidrug-Resistant Candida tropicalis Strain

Frontiers in Microbiology, 2020
Candida tropicalis is one the most relevant biofilm-forming fungal species increasingly associated with invasive mucosal candidiasis worldwide. The amplified antifungal resistance supports the necessity for more effective and less toxic treatment ...
Ari S. O. Lemos, Jônatas R. Florêncio, Nícolas C. C. Pinto, Lara M. Campos, Thiago P. Silva, Richard M. Grazul, Priscila F. Pinto, Guilherme D. Tavares, Elita Scio, Ana Carolina M. Apolônio, Rossana C. N. Melo, Rodrigo L. Fabri   +11 more
doaj   +1 more source

Evaluation of Scopoletin from Penicillium janthinellum Snef1650 for the Control of Heterodera glycines in Soybean

Life, 2021
Soybean cyst nematode (SCN) (Heterodera glycines Ichinohe) is responsible for causing a major soybean disease globally. The fungal strain Penicillium janthinellum Snef1650 was evaluated against H. glycines.
Jichen Yan, Zhifu Xing, Piao Lei, Aatika Sikandar, Ruowei Yang, Yuanyuan Wang, Xiaofeng Zhu, Xiaoyu Liu, Haiyan Fan, Yuanhu Xuan, Lijie Chen, Yuxi Duan   +11 more
doaj   +1 more source

Scopoletin: Antiamyloidogenic, Anticholinesterase, and Neuroprotective Potential of a Natural Compound Present in Roots by In Vitro and In Silico Study

Neuroscience Insights, 2020
Alzheimer’s disease (AD) is characterized by depositions of amyloid β (Aβ) peptides aggregates resulting in plaques formation in the central nervous system (CNS). This study evaluates the disease-modifying potential of scopoletin against multiple factors
Priya Kashyap, Heera Ram, Sunil Dutt Shukla, Suresh Kumar   +3 more
doaj   +1 more source