Results 61 to 70 of about 1,941 (160)

Bioactive Constituents from the Roots of Eurycoma longifolia

open access: yesMolecules, 2019
Four new phenolic components, eurylophenolosides A (1) and B (2), eurylolignanosides A (3) and B (4), along with twelve known compounds were isolated from the roots of Eurycoma longifolia Jack.
Jingya Ruan   +7 more
doaj   +1 more source

Chemical Constituents from Macaranga lowii King ex Hook.f. (Euphorbiaceae) and Their Effects on Antioxidant Activity

open access: yesASM Science Journal, 2023
The genus Macaranga comprises about 300 species worldwide and is commonly distributed in the tropical region of Africa, Southeast Asia, China and India.
AISYAH SALIHAH KAMAROZAMAN
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, Volume 40, Issue 8, Page 4792-4801, August 2026.
ABSTRACT The preclinical evidence for the safety of ashwagandha ( Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports. Most studies and reviews conclude
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Effect of Scopoletin on Apoptosis and Cell Cycle Arrest in Human Prostate Cancer Cells In vitro [PDF]

open access: yes, 2015
Purpose: To investigate the anticancer activity of scopoletin against human prostate cancer.Methods: The anticancer activity of scopoletin was evaluated by 3-(4, 5-dimethylthiazol-2-yl)-2, 5- diphenyltetrazolium bromide (MMT) assay.
Wu, JS, Li, CL, Han, XC, Zhang, H, Li, B
core   +1 more source

Rhizobacteria‐Induced Systemic Priming Against Fungal Pathogens Involves Hydroxycinnamic Acid Amides

open access: yesPlant, Cell &Environment, Volume 49, Issue 8, Page 4907-4921, August 2026.
ABSTRACT The rhizosphere, a narrow region of soil surrounding roots, contains diverse microorganisms with a composition that is distinct from the surrounding soil. Some rhizosphere bacteria can trigger a heightened state of immunity in the whole plant, termed Induced Systemic Resistance (ISR).
Mackenzie Eli William Loranger   +5 more
wiley   +1 more source

The Inhibition Kinetics and Potential Anti-Migration Activity of NQO1 Inhibitory Coumarins on Cholangiocarcinoma Cells

open access: yesIntegrative Cancer Therapies, 2019
Altered expression of a cytosolic flavoenzyme NAD(P)H:quinone oxidoreductase-1 (NQO1) has been seen in many human tumors. Its remarkable overexpression in cholangiocarcinoma (CCA; an aggressive malignancy of the biliary duct system) was associated with ...
Tueanjai Khunluck MS   +4 more
doaj   +1 more source

Comprehensive Phenolic Profiling and Antioxidant Evaluation of Calyx, Rind, and Edible Tissues From Non‐Astringent Persimmons (Diospyros kaki)

open access: yesChemistry &Biodiversity, Volume 23, Issue 7, July 2026.
Tissue‐specific phenolic profiling of non‐astringent persimmons (Fuyu and Jiro) reveals substantial differences in phytochemical composition and antioxidant potential. Persimmon calyx exhibits the highest concentrations of bioactive compounds, highlighting its potential as a valuable by‐product for functional food and nutraceutical applications ...
Huiwen Wang   +4 more
wiley   +1 more source

Effect of Noni (Morinda citrifolia Linn.) Fruit and Its Bioactive Principles Scopoletin and Rutin on Rat Vas Deferens Contractility: An Ex Vivo Study

open access: yesThe Scientific World Journal, 2014
This study examined the effect of methanolic extract of Morinda citrifolia Linn. (MMC) and its bioactive principles, scopoletin and rutin, on dopamine- and noradrenaline-evoked contractility in isolated rat vas deferens preparations.
Vijayapandi Pandy   +4 more
doaj   +1 more source

From Metabolites to Mechanisms: Scorzonera parviflora Aerial Parts and Roots Extracts Profiled by UPLC‐ESI‐MS/MS, In Vitro/In Silico Tests, and Network Analysis

open access: yesFood Science &Nutrition, Volume 14, Issue 7, July 2026.
Scorzonera parviflora is considered a promising candidate for applications in the pharmaceutical, nutraceutical, and natural product industries. ABSTRACT In the present study, the extraction of Scorzonera parviflora aerial parts and roots was performed using four solvents, namely ethyl acetate (EA), ethanol, ethanol/water, and water. The total phenolic
Gokhan Zengin   +11 more
wiley   +1 more source

SCOPOLETIN REDUCES FAT ACCUMULATION IN CAENORHABDITIS ELEGANS

open access: yes
Scopoletin, a naturally occurring coumarin, has been associated with the regulation of lipid metabolism. In this study, we used Caenorhabditis elegans, a well established in vivo nematode model, to explore the role of scopoletin in fat accumulation.
Liu, Jennifer
core   +1 more source

Home - About - Disclaimer - Privacy