FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Molecular characterization of breast cancer needle core biopsy specimens by the 21-gene Breast Recurrence Score test. [PDF]
J Surg Oncol, 2020 Jakubowski DM +9 more
europepmc +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
dearseq: a variance component score test for RNA-seq differential analysis that effectively controls the false discovery rate. [PDF]
NAR Genom Bioinform, 2020 Gauthier M +3 more
europepmc +1 more source
Test and inspection for process control of monolithic circuits [PDF]
, 1967 Report details the test and inspection procedures for the mass production of high reliability integrated circuits. It covers configuration control, basic fundamentals of quality control, control charts, wafer process evaluation, general process ...
Spangenberg, E.
core +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Statistical Method Based on Bayes-Type Empirical Score Test for Assessing Genetic Association with Multilocus Genotype Data. [PDF]
Int J Genomics, 2020 Tian Y, Ma L, Cai X, Zhu J.
europepmc +1 more source
TEST CONSTRUCTION MANIPULATING SCORE DIFFERENCES BETWEEN BLACK AND WHITE EXAMINEES: PROPERTIES OF THE RESULTING TESTS [PDF]
, 1987 Rachelle K. Hackett +3 more
openalex +1 more source
Development and testing quantitative metrics from multi-parametric magnetic resonance imaging that predict Gleason score for prostate tumors [PDF]
, 2021 Rulon Mayer +3 more
openalex +1 more source