Results 81 to 90 of about 10,029 (219)
Insect- and vertebrate-selective neurotoxins from Australian urodacid and buthid scorpion venoms : lead compounds for novel biopesticides [PDF]
University of Technology, Sydney. Department of Health Sciences.Scorpions from nine species were collected from locations across Australia comprising four Lychas (Buthidae), four Urodacus (Urodacidae) and one Cercophonius (Bothriuridae) .
Wilson, HL
core
Background: Toxinology is a field of toxicology involved in studying toxins from animals, plants and microorganisms. In Colombia, in last thirty years, this area has been mainly studied by Programa de Ofidismo/Escorpionismo of the Universidad de ...
Jaime Andrés Pereañez +2 more
doaj +1 more source
Role of Antimicrobial Peptides in the Pathogenesis of Atopic Dermatitis
ABSTRACT Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by barrier dysfunction, immune dysregulation, and microbial dysbiosis. Recent studies have highlighted the multifaceted roles of antimicrobial peptides (AMPs) both as innate defenders against microbial invasion and as regulators of immune responses and skin barrier ...
Ge Peng +9 more
wiley +1 more source
Molecular basis for heat desensitization of TRPV1 ion channels. [PDF]
The transient receptor potential vanilloid 1 (TRPV1) ion channel is a prototypical molecular sensor for noxious heat in mammals. Its role in sustained heat response remains poorly understood, because rapid heat-induced desensitization (Dh) follows ...
Kamau, Peter Muiruri +8 more
core +2 more sources
The venoms of Buthidae scorpions are known to contain basic, single-chain protein -toxins consisting of 60-70 amino acid residues that are tightly cross-linked by four disulfide bridges.
Eskandari, Gh., +3 more
doaj
The nociceptive properties of differentiated human HD10.6 cells were characterized by multiple approaches (A). Peripheral sensitization was induced within HD10.6 cells in response to an inflammatory cocktail (B), modeling nociceptors in a chronic pain state.
Sara A. Dochnal +11 more
wiley +1 more source
Hemiscorpius lepturus (H. lepturus) which belongs to the Scorpionidae family, is the deadliest scorpion in Iran. It causes pathological manifestations like dermonecrosis, hemolysis, renal failure, necrotic ulcers, and in some cases, even death. The venom
Abouzar Soleimani Moez +4 more
doaj +1 more source
The sequence expression and immunological characterisation of the HT-1 neurotoxin from the Australian paralysis tick Ixodes holocyclus [PDF]
University of Technology Sydney. Faculty of Science.The paralysis tick of Australia, Ixodes holocyclus, causes a severe toxicosis in domestic animals such as dogs and cats, livestock, and in some cases humans.
Masina, Slavica
core
Structural Basis of the Selective Block of Kv1.2 by Maurotoxin from Computer Simulations
The 34-residue polypeptide maurotoxin (MTx) isolated from scorpion venoms selectively inhibits the current of the voltage-gated potassium channel Kv1.2 by occluding the ion conduction pathway. Here using molecular dynamics simulation as a docking method,
Chen, Rong, Chung, Shin-Ho
core +1 more source
Transcriptome annotation and characterization of novel toxins in six scorpion species
Background Venom has evolved in parallel in multiple animals for the purpose of self-defense, prey capture or both. These venoms typically consist of highly complex mixtures of toxins: diverse bioactive peptides and/or proteins each with a specific ...
Dwin G. B. Grashof +7 more
doaj +1 more source

