Results 61 to 70 of about 146,692 (204)
Functional evolution of scorpion venom peptides with an inhibitor cystine knot fold
Bioscience Reports, 2013 The ICK (inhibitor cystine knot) defines a large superfamily of polypeptides with high structural stability and functional diversity. Here, we describe a new scorpion venom-derived K+ channel toxin (named λ-MeuKTx-1) with an ICK fold through gene ...
Bin Gao +5 more
doaj +1 more source
Proteomic endorsed transcriptomic profiles of venom glands from Tityus obscurus and T. serrulatus scorpions. [PDF]
PLoS ONE, 2018 Except for the northern region, where the Amazonian black scorpion, T. obscurus, represents the predominant and most medically relevant scorpion species, Tityus serrulatus, the Brazilian yellow scorpion, is widely distributed throughout Brazil, causing ...
Ursula Castro de Oliveira +9 more
doaj +1 more source
[Scorpion toxins and defensins].
Comptes rendus des seances de la Societe de biologie et de ses filiales, 1998 Les venins de scorpion contiennent un grand nombre de neurotoxines peptidiques qui constituent un ensemble de familles moléculaires à haut degré de polymorphisme, mais qui ont en commun une architecture semblable. Cette architecture se retrouve dans des peptides antibactériens circulants de la famille des défensines, qui s'apparentent tout ...
Goyffon, M, Landon, C.
openaire +2 more sources
Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.This study investigates the phytochemical profile and biological potential of Atriplex halimus L. and Marrubium deserti De Noé extracts. Polyphenolic constituents are identified using UHPLC‐MS/MS analysis, complemented by TPC and TFC evaluations. Antioxidant activities are determined via DPPH, ABTS, and FRAP assays, while antimicrobial efficacy is ...
Nacira Siad +9 more
wiley +1 more source
Acta Cirúrgica Brasileira, 2004 PURPOSE: Scorpion toxin purified from Tityus serrulatus venom (Tx) induces an increase in volume, acidity and pepsin secretion in the gastric juice of rats. Ligation of oesophagus has been shown to reduce the acid gastric secretion in rats.
Claudia S. Vidal +6 more
doaj +1 more source
Scorpion toxins specific for Na+‐channels [PDF]
European Journal of Biochemistry, 1999 Na+‐channel specific scorpion toxins are peptides of 60–76 amino acid residues in length, tightly bound by four disulfide bridges. The complete amino acid sequence of 85 distinct peptides are presently known. For some toxins, the three‐dimensional structure has been solved by X‐ray diffraction and NMR spectroscopy.
Possani, Lourival D. +3 more
openaire +3 more sources
Spinal Anesthesia Failure Following Wasp Envenomation: A Case Series of Two Patients
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Spinal anesthesia is highly effective, and complete failure in healthy patients is rare. Wasp venom contains neuroactive peptides capable of modifying sodium‐channel function and inducing neuroinflammation, but its impact on neuraxial anesthesia has not been previously reported. We describe two healthy ASA I males who developed complete spinal
Ammir Abuzahra +8 more
wiley +1 more source
Bioactive peptides in cancer and inflammation: Mechanisms, model systems and clinical translation
Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.Bioactive peptides (BAPs) derived from host, marine, insect, plant and synthetic sources share cationic, amphipathic structures adopting α‐helical, β‐sheet or cyclic conformations. These features underlie anti‐cancer effects, including membrane disruption, apoptosis and cell‐cycle arrest, anti‐metastatic activity, reduced invasion and migration, and ...
Najwa Doha +4 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 10, October 2026.This review contrasts the root and leaf of Withania somnifera (ashwagandha) across phytochemistry, clinical evidence, and regulatory context. Root preparations are dominated by withanolide A, D, and glyco‐withanolides, with multiple randomized controlled trials supporting reductions in stress, anxiety, and insomnia alongside a favorable safety profile.
Abhijit Dutta, Jang Bahadur Gupta
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.ABSTRACT Background Sarcopenia, a loss of muscle strength, quantity and performance that occurs primarily from ageing or secondary to disease, is hypothesized to worsen treatment outcomes in patients with cancer. Most published studies, however, focus solely on muscle quantity in patients under 70.
Lindsey J. Mattick +18 more
wiley +1 more source