Results 91 to 100 of about 356,030 (194)

Evaluation of separation properties of a modified strong cation exchange material named MEX and its application in 2D-MEX x C18 system to separate peptides from scorpion venom

, 2015
Peptides from scorpion venom represent one of the most promising drug sources for drug discovery for some specific diseases. Current challenges in their separation include high complexity, high homologies and the huge range of peptides.
Jin, Yu, Liang, Xinmiao, Guo, Zhimou, Dong, Xuefang, Chen, Bo, Fu, Qing, Xu, Junyan   +6 more
core   +1 more source

Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors [PDF]

, 2013
Venoms from cone snails (Conidae) have been extensively studied during the last decades, but those from other members of the suborder Toxoglossa, such as of Terebridae and Turridae superfamilies attracted less interest so far. Here, we report the effects
Wunder, C., Peigneur, S., Silke Kauferstein, Melaun, Christian, Annette Nicke, Nicke, Annette, Dietrich Mebs, Christian Melaun, Peigneur, Steve, Kauferstein, S., Kauferstein, Silke, Wunder, Cora, Kendel, Y., Mebs, D., Kurz, A., Steve Peigneur, Tytgat, Jan, Melaun, C., Kendel, Yvonne, Kurz, Alexander, Mebs, Dietrich, Yvonne Kendel, Jan Tytgat, Cora Wunder, Alexander Kurz, Nicke, A., Tytgat, J.   +26 more
core   +1 more source

Activity of Scorpion Venom-Derived Antifungal Peptides against Planktonic Cells of Candida spp. and Cryptococcus neoformans and Candida albicans Biofilms [PDF]

, 2016
The incidence of fungal infections has been increasing in the last decades, while the number of available antifungal classes remains the same. The natural and acquired resistance of some fungal species to available therapies, associated with the high ...
Octávio L. Franco, Pedro Henrique S. Costa, Sônia M. Freita, Andre Moraes Nicola, Patrícia Albuquerque, Pereira, Ildinete Silva, Nathália Vilela, Anamelia Lorenzetti Bocca, Albuquerque, Patrícia, Anamélia L. Bocca, Márcia Renata Mortari, Vilela, Nathália, Mortari, Márcia Renata, Smidt, Karina S., André M. Nicola, Marco Antonio de Oliveira, Sônia M. de Freitas, Franco, Octávio Luiz, Aldo H. Tavares, Freitas, Sônia Maria de, Maria Célia L. Rigonatto, Guilhelmelli, Fernanda, Derengowski, Lorena da Silveira, Márcia R. Mortari, Alice CM Álvares, Karina S. Simon, Costa, Pedro Henrique Silva, Oliveira, Marco Antônio de, Octavio Luiz Franco, Lorena S. Derengowski, Nicola, André Moraes, Marco A. de Oliveira, Alice da Cunha Morales Álvares, Elisabeth F. Schwartz, Álvares, Alice da Cunha Morales, Schwartz, Elisabeth Nogueira Ferroni, Rigonatto, Maria Célia Larangeira, Fernanda Guilhelmelli, Maria C. L. Rigonatto, Karina S. Smidt, Lorena da Silveira Derengowski, Ildinete Silva-Pereira, Pedro H. da Silva Costa, Bocca, Anamélia Lorenzetti, Tavares, Aldo Henrique   +44 more
core   +1 more source

Beta Toxins Isolated from the Scorpion Centruroides hirsutipalpus (Scorpiones; Buthidae) Affect the Function of Sodium Channels of Mammals

Toxins
Scorpion venom toxins are important peptides being studied for their clinical significance. These peptides act by binding to ion channels in the membrane of nerve cells, causing the symptoms associated with scorpion stings (scorpionism). They principally
Laura L. Valdez-Velazquez, Timoteo Olamendi-Portugal, Rita Restano-Cassulini, Lidia Riaño-Umbarila, Juana María Jiménez-Vargas, Fernando Zamudio, Hermenegildo Salazar-Monge, Baltazar Becerril, Lourival D. Possani   +8 more
doaj   +1 more source

Overview of Scorpion Species from China and Their Toxins

Toxins, 2014
Scorpions are one of the most ancient groups of terrestrial animals. They have maintained a steady morphology over more than 400 million years of evolution.
Zhijian Cao, Zhiyong Di, Yingliang Wu, Wenxin Li   +3 more
doaj   +1 more source

Scorpion Venom as a Source of Cancer Drugs: A Comprehensive Proteomic Analysis and Therapeutic Potential

Scorpion venom is a rich source of bioactive compounds with significant potential for anticancer drug development. Its diverse molecular composition, including neurotoxins, antimicrobial peptides, and enzymes, provides a vast library for therapeutic ...
Kimberly Borges Evangelista, Stephanie Santos Suehiro Arcos, Mariana Ramos da Cunha Aguiar, Júlia de Oliveira, Gustavo Henrique Rohr Souza Machado, Isabela de Oliveira Cavalcante Pimentel, Matheus Ramos da Silva, Fernanda Calheta Vieira Portaro, Leo Kei Iwai, Nicolas Gamboa dos Anjos   +9 more
core   +1 more source

Profiling the resting venom gland of the scorpion Tityus stigmurus through a transcriptomic survey

BMC Genomics, 2012
Background The scorpion Tityus stigmurus is widely distributed in Northeastern Brazil and known to cause severe human envenoming, inducing pain, hyposthesia, edema, erythema, paresthesia, headaches and vomiting.
Almeida Diego D, Scortecci Katia C, Kobashi Leonardo S, Agnez-Lima Lucymara F, Medeiros Silvia R B, Silva-Junior Arnóbio A, Junqueira-de-Azevedo Inácio, Fernandes-Pedrosa Matheus   +7 more
doaj   +1 more source

Scorpion Venom: New Promise in the Treatment of Cancer [PDF]

, 2019
Cancer is a public health problem due to its high worldwide morbimortality. Current treatment protocols do not guarantee complete remission, which has prompted to search for new and more effective antitumoral compounds.
Carlos Corredor Pereira, Lyz Jenny Gómez Rave, Corredor Pereira, Carlos, Laura Melisa Román Marín, Sierra-Castrillo, Jhoalmis, Román Marín, Laura-Melisa, Jhoalmis Sierra Castrillo, Adriana Ximena Muñoz Bravo, Gómez Rave, Lyz Jenny, Muñoz Bravo, Adriana Ximena, Sierra Castrillo, Jhoalmis, Román Marín, Laura Melisa   +11 more
core   +1 more source

Whole Transcriptome of the Venom Gland from Urodacus yaschenkoi Scorpion.

PLoS ONE, 2015
Australian scorpion venoms have been poorly studied, probably because they do not pose an evident threat to humans. In addition, the continent has other medically important venomous animals capable of causing serious health problems.
Karen Luna-Ramírez, Verónica Quintero-Hernández, Víctor Rivelino Juárez-González, Lourival D Possani   +3 more
doaj   +1 more source

Snapshots of scorpion venomics

, 2015
Scorpions are particularly well adapted to survival in extreme habitats (especially arid and semi-arid environments) and their ability to produce and deliver venoms is an important factor in this success.
Abdel-Rahman, Mohamed A., Harrison, Patrick L., Strong, Peter   +2 more
core   +1 more source