Venomics of Remipede Crustaceans Reveals Novel Peptide Diversity and Illuminates the Venom’s Biological Role [PDF]
© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Björn von Reumont+14 more
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Identification and Characterization of a Novel GAPDH‐Derived Antimicrobial Peptide From Jellyfish
A novel GAPDH‐derived peptide JFP‐2826, which showed selective antimicrobial activity against marine‐specific Vibrio bacteria, was identified from the transcriptome of Rhopilema esculentum. Jellyfish GAPDH may have a newly discovered antimicrobial‐related function conducted by releasing JFP‐2826‐like cryptic peptides. ABSTRACT Marine organisms serve as
Jingwen Liu+9 more
wiley +1 more source
The 6th international conference on envenomation by snakebites and scorpion stings in Africa : a crucial step for the management of envenomation [PDF]
During the 6th International Conference on Envenomation by Snakebites and Scorpion Stings in Africa held in Abidjan, from 1 to 5 June 2015, the measures for the management of envenomation were discussed and new recommendations were adopted by the ...
Akaffou, M. H.+5 more
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Inhibition of cGMP‐Signalling Rescues Retinal Ganglion Cells From Axotomy‐Induced Degeneration
Retinal ganglion cell (RGC) axons are myelinated only beyond the lamina cribrosa, that is, when leaving the eye. Axotomy‐induced RGC degeneration is likely to be related to excessive nitric oxide (NO) production, leading to an over‐production of cGMP, over‐activation of protein kinase G (PKG) and excessive phosphorylation of target proteins, such as ...
Katia Ihadadene+4 more
wiley +1 more source
Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami [PDF]
The inexorable decline in the armament of registered chemical insecticides has stimulated research into environmentally-friendly alternatives. Insecticidal spider-venom peptides are promising candidates for bioinsecticide development but it is ...
Bosmans, F+10 more
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Antigenic Cross-Reactivity Anti-Birtoxin Antibody against Androctonus crassicauda Venom
Background: Antivenom is still widely used in the treatment of envenomation as there are no vaccines or other effective agents available against animal venoms.
SuhandanAdigüzel Van-Zoelen+2 more
doaj
Subtype Specificity of β-Toxin Tf1a from Tityus fasciolatus in Voltage Gated Sodium Channels
Scorpion venoms are a complex mixture of components. Among them the most important are peptides, which presents the capacity to interact and modulate several ion channel subtypes, including voltage-gated sodium channels (NaV).
Daniel Oliveira da Mata+6 more
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Interrogating stonefish venom: small molecules present in envenomation caused by Synanceia spp.
Molecular analysis of Synanceia horrida (ShV) and S. verrucosa (SvV) venoms identified three small molecules new to stonefish venom: Gamma‐aminobutyric acid (GABA), choline, and 0‐acetylcholine. Analysis on human nicotinic acetylcholine (nAChRs) and GABAA receptors showed activation of neuronal (α7) and adult muscle‐type (α1β1δε) nAChRs by ShV, while ...
Silvia Luiza Saggiomo+4 more
wiley +1 more source
Structure-function strategies to improve the pharmacological value of animal toxins. [PDF]
ISBN : 978-0-12-369442-3Animal venoms are rich sources of bioactive compounds that possess obvious pharmacological, therapeutic and/or biotechnological values.
de Waard, Michel, Sabatier, Jean-Marc
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Venom gland transcriptomic and proteomic analyses have improved our knowledge on the diversity of the heterogeneous components present in scorpion venoms. However, most of these studies have focused on species from the family Buthidae.
Carlos E. Santibáñez-López+4 more
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