Results 51 to 60 of about 583,399 (327)

Computational thinking in the curricular component of mathematics in basic education: Possibilities and challenges

open access: yesInternational Journal of Trends in Mathematics Education Research, 2023
This article highlights and discusses aspects of the perceptions of a group of Mathematics teachers in Basic Education about Computational Thinking (CT) and its possibilities of working simultaneously with the curricular component of Mathematics in Basic
Janice Teresinha Reichert, Milton Kist
doaj   +1 more source

Experimental and numerical study on scratching test [PDF]

open access: yes, 2013
This paper presents recent investigation of the material removal mechanism in single grit grinding test. Single grit scratches were generated experimentally by using CBN grit on En24T steel and compared with numerical simulation by using finite element ...
Chen, Xun, Öpöz, Tahsin
core  

Creating R Packages: A Tutorial [PDF]

open access: yes, 2008
This tutorial gives a practical introduction to creating R packages. We discuss how object oriented programming and S formulas can be used to give R code the usual look and feel, how to start a package from a collection of R functions, and how to test ...
Brito, Paula, Leisch, Friedrich
core   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Synergic Effects of Nanosecond Laser Ablation and PVD-Coating on Cemented Carbides: Assessment on Surface and Mechanical Integrity

open access: yesMetals, 2023
Emerging laser precision machining, particularly using pulsed lasers, enlightens the innovation and functionalization of cemented carbides. These backbone materials of the tooling industry are usually considered difficult to machine or shape using ...
Shiqi Fang   +3 more
doaj   +1 more source

When Developing a Career Path, What are the Key Elements to Include? [PDF]

open access: yes, 2013
Question: When developing a career path from scratch, what are the key elements to include in the design process and what factors lead to a successful ...
Cao, Jing, Thomas, Desiree
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Programlama Öğretim Sürecinde Üstün Yetenekli İlkokul Öğrencilerinin Görüşlerinin İncelenmesi

open access: yesAnkara Üniversitesi Eğitim Bilimleri Fakültesi Dergisi, 2019
Programlama etkinliklerinin erken yaşta deneyimlenmesi gün geçtikçe önem kazanan bir konudur. Bu çalışmada ilkokul 2., 3. ve 4. sınıfta öğrenim gören 26 üstün yetenekli öğrenci ile Scratch destekli programlama öğretimine yönelik 15 haftalık bir uygulama ...
Hatice Yıldız Durak, Tolga Güyer
doaj   +1 more source

Perceptual Abstraction for Robotic Cognitive Development [PDF]

open access: yes, 2003
We are concerned with the design of a developmental robot that learns from scratch simple models about itself and its surroundings.
Driancourt, Remi
core  

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