Results 51 to 60 of about 586,826 (328)
FRICTION ANALYSIS ON SCRATCH DEFORMATION MODES OF VISCO-ELASTIC-PLASTIC MATERIALS
Reaktor, 2013 Understanding of abrasion resistance and associated surfaces deformation mechanisms is of primary importance in materials engineering and design. Instrumented scratch testing has proven to be a useful tool for characterizing the abrasion resistance of ...
Budi Setiyana +3 more
doaj +1 more source
Creating R Packages: A Tutorial [PDF]
, 2008 This tutorial gives a practical introduction to creating R packages. We discuss how object oriented programming and S formulas can be used to give R code the usual look and feel, how to start a package from a collection of R functions, and how to test ...
Brito, Paula, Leisch, Friedrich
core +2 more sources
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Em Extensão, 2022 A tecnologia está cada vez mais presente no cotidiano das pessoas, portanto, torna- se um importante recurso no processo de ensino e aprendizagem, com possibilidade de adoção não apenas em contextos específicos de cunho tecnológico, mas também em ...
Amanda Karollyne Monteiro Rodrigues +2 more
doaj +1 more source
Agent-based computational modeling of wounded epithelial cell monolayers [PDF]
, 2004 Computational modeling of biological systems, or ‘in silico biology’ is an emerging tool for understanding structure and order in biological tissues. Computational models of the behavior of epithelial cells in monolayer cell culture have been developed ...
Hill, G. +4 more
core +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Educación a distancia. Reto de la superación a través del curso Algoritmización con Scratch
Serie Científica de la Universidad de las Ciencias Informáticas, 2021 Los profesionales de informática y ramas afines reciben actividades de superación a través de la modalidad a distancia. La educación a distancia con el uso de las Tecnologías de la Información y las Comunicaciones (TIC), es una necesidad para la ...
Yor Alex Remond Recio +1 more
doaj
Gamification with Scratch or App Inventor in Higher Education: A Systematic Review
Future Internet, 2022 Programming skills should be taught and developed; Scratch and App Inventor are two tools that can contribute significantly to developing this competence in university students.
David Pérez-Jorge +1 more
doaj +1 more source
Starting from scratch: experimenting with computer science in Flemish secondary education [PDF]
, 2014 In the Flemish secondary education curriculum, as in many countries and regions, computer science currently only gets an extremely limited coverage. Recently, in Flanders (and elsewhere), it has been proposed to change this, and try-outs are undertaken ...
Lemmens, Stefan +2 more
core +2 more sources