Results 191 to 200 of about 907,996 (252)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Digital behavior and anxiety in the post-pandemic era: a five-year analysis of screen time, sleep, and behavioral risk profiles. [PDF]

Front Public Health
Liu W.
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Associations of dietary patterns and screen time with depressive symptoms among adolescents in Shandong Province, China. [PDF]

BMC Public Health
Jiang X, Li Z, Wen P, Ling Y, Li H, Huang J.   +5 more
europepmc   +1 more source

Associations of Sleep, Screen Time, and Extracurricular Activities With Cognitive Development: A Longitudinal Study. [PDF]

J Adolesc
Zheng J, Berg E, Byrne ML, Rakesh D.
europepmc   +1 more source

The association between parental mental health and screen time among U.S. children aged 6-17. [PDF]

BMC Psychol
Qiu S, Cao Y, Chen S, Li G, Liu Y, Wang Y, Zeng X, Yuan M, Yang W.   +8 more
europepmc   +1 more source

Knowledge, Perceptions and Attitude Towards Effect of Screen Time among Undergraduate Students.

J Pharm Bioallied Sci
Pant M, Salman L, Betigeri AV, Sangi H, Widge H, Raj H.   +5 more
europepmc   +1 more source

Impact of Screen Time on Language Development and Vocabulary Acquisition in Early Childhood: A Systematic Review. [PDF]

Cureus
Nwachukwu EC, Nigam A, Sekar Lakshmisai S, Sakarkar P, Bheemaneni RS, Malasevskaia IA.   +5 more
europepmc   +1 more source

Associations of Problematic Smartphone Use and Smartphone Screen Time With Eating Disorder Psychopathology in Non-Clinical Samples: A Systematic Review.

JMIR Ment Health
Keeler J, Conde Ludtke L, Yang Q, Raschke Rameh V, Ward R, Treasure J, Carter B.   +6 more
europepmc   +1 more source