TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng +9 more
wiley +1 more source
Elastic Energy Storage in Al-Al<sub>4</sub>C<sub>3</sub> Composites: Effects of Dislocation Character and Interfacial Graphite Formation. [PDF]
Santos Beltrán A +8 more
europepmc +1 more source
Single‐Crystalline Borate Covalent Organic Frameworks for Solid‐State Lithium Metal Batteries
Advancing lithium metal batteries demands novel solid‐state electrolytes. Covalent organic frameworks (COFs) offer high ion conduction via porosity and functional groups. We synthesized single‐crystalline 3D borate COF with 8.1 mS cm−1 conductivity and 0.98 Li+ transference.
Ye Tian +12 more
wiley +1 more source
Regulating Extruded Expanded Food Quality Through Extrusion Die Geometry and Processing Parameters. [PDF]
Zhang Q +5 more
europepmc +1 more source
OPTRACE: Optical Imaging–Guided Transplantation and Tracking of Cells in the Mouse Brain
OPTRACE establishes an optical, two‐step platform for intracerebral cell therapy. Transparent glass pipettes enable real‐time, image‐guided delivery, while multiplex genetic labeling with two‐photon and bioluminescence readouts supports longitudinal single‐cell tracking and host–graft dynamics.
Jinghui Wang +10 more
wiley +1 more source
Nickel-Catalyzed Cross-Coupling of Aryl Chlorides by Heated Mechanochemistry: Scalable Suzuki-Miyaura Reactions via Twin-Screw Extrusion. [PDF]
Raby-Buck SE +5 more
europepmc +1 more source
This study demonstrates multimodal integration in non‐human primates, combining large‐scale, high‐density electrophysiology using Smart Dura with optical techniques such as multiphoton imaging (MPI), photothrombotic lesioning, optical coherence tomography angiography (OCTA), wide‐field intrinsic signal optical imaging (ISOI), and optogenetics.
Nari Hong +10 more
wiley +1 more source
Measurement study of the "optimal" screw axis location and its angles with the first and second metacarpals based on X imaging of the scaphoid bone. [PDF]
Guo J +5 more
europepmc +1 more source
Stretchable Curvature Sensors for Motion Capture with Bending‐Stretching Coupling Deformation
Stretchable curvature sensors based on a wavy symmetric stacked‐layer structure (WSSLS) enable decoupled bending‐stretching detection with high linearity, repeatability, and durability. Integrated into smart gloves, the sensors achieved precise motion capture and human‐robot interaction, with slip‐simulation tests demonstrating a remarkable 93.6 ...
Tairan Wang +9 more
wiley +1 more source
Letter to the Editor: comment on "Arthroscopic suspension fixation for acute posterior cruciate ligament avulsion fractures in adolescents: a retrospective cohort study". [PDF]
Chen G, Chen Y, Xu W.
europepmc +1 more source

