Results 51 to 60 of about 198,576 (265)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

An ‘Attracted’ Script [PDF]

open access: yesThe English Historical Review, 1921
n ...
openaire   +1 more source

If the script doesn’t work, change the script

open access: yesEducation Review, 2022
Every career is different, emerging from different circumstances and almost always influenced by unforeseen opportunities and challenges. The script we write will be revised and edited many times. I have found my script changing at important junctures in my career.
openaire   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

MINAT BELAJAR AKSARA LOKAL SASAMBO MAHASISWA PGSD UNIVERSITAS MATARAM

open access: yesPrimary: Jurnal Pendidikan Guru Sekolah Dasar, 2020
Local scripts are the priceless cultural heritage of the nation. The existence of local scripts today is increasingly eroded by the use of Latin writing. A few young people are able to write local scripts.
Arif Widodo   +4 more
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Sparks Will Fly: engineering creative script conflicts

open access: yesConnection Science, 2017
Scripts are often dismissed as the stuff of good movies and bad politics. They codify cultural experience so rigidly that they remove our freedom of choice and become the very antithesis of creativity.
Tony Veale, Alessandro Valitutti
doaj   +1 more source

THE INTEREST OF LEARNING LOCAL SCRIPT SASAMBO OF PGSD STUDENTS AT UNIVERSITY OF MATARAM

open access: yesPrimary: Jurnal Pendidikan Guru Sekolah Dasar, 2020
Local scripts are the priceless cultural heritage of the nation. The existence of local scripts today is increasingly eroded by the use of Latin writing. A few young people are able to write local scripts.
Arif Widodo   +4 more
doaj   +1 more source

Script Geometry

open access: yes, 2016
In this paper we describe the foundation of a new kind of discrete geometry and calculus called Script Geometry. It allows to work with more general meshes than classic simplicial complexes. We provide the basic definitions as well as several examples, like the Klein bottle and the projective plane.
Cerejeiras, Paula   +3 more
openaire   +4 more sources

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz   +3 more
wiley   +1 more source

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