Results 101 to 110 of about 6,639,635 (250)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

sd

, 2021
Sd-locus, conferring resistance to rosy leaf-curling aphid, was detected in the collection of 132 apple accessions. Sd-locus was identified in genomes of 31 apple cultivars and hybrids of breeding performed Belarus, Russian, Ukraine, Germany, etc. The molecular marker technology was used for developing promising apple hybrid seedling resistant to rosy ...
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Trust and glycemic control in black patients with diabetic retinopathy: A pilot study [PDF]

, 2019
Diabetic retinopathy (DR) is more prevalent in blacks than whites because, compared to whites, blacks on average have worse glycemic control. Both of these racial disparities reflect differences in sociocultural determinants of health, including ...
Casten, Robin J., Rovner, Barry W.
core   +1 more source

Magnetic dipole probes of the sd and pf shell crossing in the A=36,38 argon isotopes

, 2006
We have calculated the M1 strength distributions in the A=36,38 argon isotopes within large-scale shell model studies which consider valence nucleons in the sd and pf shells.
A. Richter, A.F. Lisetskiy, Brown, Caurier, Caurier, Caurier, Chittrakarn, Dean, E. Caurier, F. Nowacki, Foltz, G. Martínez-Pinedo, Gaarde, Gross, K. Langanke, Kahana, Langanke, Li, Marinez-Pinedo, Motobayashi, Navratil, Nummela, P. von Neumann-Cosel, Park, Poves, Retamosa, Schielke, von Neumann-Cosel, Warburton, Zheng   +29 more
core   +3 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

PENINGKATAN PEMAHAMAN KONSEP MATEMATIKA MELALUI MODEL PROJECT BASED LEARNING

Paedagoria
Abstrak: Pemahaman terkait materi perkalian dan pembagian pecahan adalah konsep materi yang sulit bagi siswa kelas IV SDN 3 CEMAGI. Hal ini di tunjukkan dari rendahnya hasil capaian belajar yang rata-rata dibawah Kriteria Ketuntasan Minimal (KKM ...
I Gede Heri Pilawinata, I Dewa Kadek Putrayasa, I Putu Agus Suryadi, I Nyoman Sukerta Yasa, Sukaesi Sukaesi, Nursina Sari   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Nano Oil Additive Improves Internal Combustion Engine Efficiency and Life Expectancy

Lubricants
Internal combustion engines remain a predominant source of global energy consumption, contributing substantially to both operational costs and greenhouse gas emissions.
Ding Lou, Jordan Morrison, Greg Christensen, Craig Bailey, Rose Gerani, Aaron Nardi, Rob Hrabe   +6 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source