Results 71 to 80 of about 6,568,873 (280)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Feasibility of the modified sequential organ function assessment score in a resource-constrained setting: a prospective observational study. [PDF]
, 2017 BackgroundSub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in assessing morbidity and mortality in ...
Ejoku, Joseph +8 more
core +2 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
, 2021 Sd-locus, conferring resistance to rosy leaf-curling aphid, was detected in the collection of 132 apple accessions. Sd-locus was identified in genomes of 31 apple cultivars and hybrids of breeding performed Belarus, Russian, Ukraine, Germany, etc. The molecular marker technology was used for developing promising apple hybrid seedling resistant to rosy ...
openaire +3 more sources
'n Struktureel-historiese eksegese van Habakuk 1:2-2:4
Acta Theologica, 1996 In this article Hab 1:2-2:4 is subjected to a structural-historical exegesis. This means that both the text intern aspects (demarcation of the pericope, text critical matters and a structural analysis) and the text extern aspects (Gattung, Sitz im Leben,
SD Snyman
doaj +1 more source
, 2012 The presentation of the ALD’s 50th Anniversary Medal to Jennifer Tipton could hardly have taken place in a more appropriate location in terms of the history of British lighting design. The Hampstead Conservatoire of Music – now the Embassy Theatre at the
Palmer, SD
core
, 1992 Plants of Begonia x tuberhybrida ‘Nonstop’, ‘Clips’, and ‘Musical’ were exposed to 1, 2, 3, or 4 weeks of short days (SD, 9 hours day length) initiated at 3 stages of plant development (immediately upon germination, 4 or 8 weeks after germination ...
Karlsson, Meriam G., Werner, Jeffrey W.
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
İstanbul Gelişim Üniversitesi Sosyal Bilimler DergisiIn recent years, social pressure on the measures taken or to be taken on the environment has been increasing, especially in developed and developing countries.
Nuh Keleş
doaj +1 more source
Divine and human violence and destruction in Jeremiah 20:7-13
Acta Theologica, 1999 Jeremiah 20:7-13 is a text presenting the interpreter with a multitude of problems. Five main areas of research are briefly highlighted. This paper focuses on the interpretation of hamas wasod in Jer 20:8.
SD Snyman
doaj +1 more source