Remission versus low disease activity as treatment targets in rheumatoid arthritis: how to strike the right balance between too strict and too lenient targets? A meta-epidemiological study of individual patient data [PDF]
RMD OpenObjectives To evaluate the impact of using Simplified Disease Activity Index (SDAI)-LDA (low disease activity) versus different definitions of remission as a treatment target in established rheumatoid arthritis.Methods A meta-epidemiological study of ...
Désirée van der Heijde +7 more
doaj +5 more sources
Evaluation of the clinical efficiency of tocilizumab therapy, by using DAS 28, SDAI, CDAI indices and new 2011 EULAR/ACR remission criteria in patients with rheumatoid arthritis [PDF]
Научно-практическая ревматология, 2012 Objective: to evaluate the clinical efficiency of tocilizumab (TCZ) from the DAS 28, SDAI, and CDAI indices and to estimate remission rates from the European League Against Rheumatism (EULAR) criteria, and the new remission criteria proposed by the EULAR
Anastasia Sergeyevna Avdeyeva +3 more
doaj +2 more sources
A comparison between the Simplified Disease Activity Index (SDAI) and the Disease Activity Score (DAS28) as measure of response to treatment in patients undergoing different therapeutic regimens [PDF]
Reumatismo, 2011 Objective: To compare the SDAI values to DAS28 scores in RA patients undergoing different DMARD regimens. Methods: The SDAI is an unweighted numerical sum of five outcome parameters: tender and swollen joint count (based on 28-joint assessment), patient ...
Gabriele Valentini +4 more
doaj +2 more sources
Short‐Interval Discordance Between Fatigue and Joint Counts in Rheumatoid Arthritis [PDF]
Int J Rheum DisInternational Journal of Rheumatic Diseases, Volume 29, Issue 10, October 2026.
Yidi Huang +4 more
wiley +2 more sources
Journal of Clinical Rheumatology and ImmunologyBackground Rheumatoid arthritis (RA) is a chronic inflammatory disease with progressive joint destruction. High-resolution peripheral quantitative CT (HR-pQCT) is a novel technique for detailed bone microstructure analysis allowing volumetric assessment ...
Qihan Wu +5 more
doaj +2 more sources
Are global definitions enough? Revisiting CDAI and SDAI remission cut-offs in Brazilian Rheumatoid Arthritis patients [PDF]
Advances in RheumatologyBackground Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease in which achieving remission is the most effective strategy to prevent progression and optimize long-term outcomes.
Lucas Castro Pires +16 more
doaj +2 more sources
Temporal Patterns of Outcomes After DMARD Tapering or Withdrawal in Rheumatoid Arthritis With Sustained Disease Control: A Systematic Review and Meta‐Analysis [PDF]
Clinical and Translational Science, Volume 19, Issue 10, October 2026.ABSTRACT Rheumatoid arthritis (RA) requires lifelong treatment with disease‐modifying antirheumatic drugs (DMARDs). In patients with sustained disease control, DMARD de‐escalation has been proposed to lessen treatment burden, but its efficacy and safety remain elusive.
Xiaoyan Zhang +3 more
wiley +2 more sources
Partial bone erosion repair is independently associated with functional improvement in early rheumatoid arthritis: a 2-year prospective high-resolution peripheral quantitative CT (HR-pQCT) longitudinal study [PDF]
RMD OpenObjective To determine whether change in bone erosion volume detected by high-resolution peripheral quantitative CT (HR-pQCT) is independently associated with functional outcome in early rheumatoid arthritis (ERA).Methods In this prospective study, 101 ...
Ling Qin +15 more
doaj +2 more sources
Effects of achieving simple disease activity index remission on joint space outcomes progression in early rheumatoid arthritis: an exploratory study using high-resolution peripheral quantitative computed tomography [PDF]
Therapeutic Advances in Musculoskeletal DiseaseBackground: Rheumatoid arthritis is a chronic inflammatory disease with progressive joint destruction resulting in functional loss. High-resolution peripheral quantitative CT (HR-pQCT) is a novel technique for detailed volumetric assessment of joint ...
Qihan Wu +15 more
doaj +2 more sources
Arthritis Research & Therapy, 2018 Background The aim was to analyze characteristics that predict remission induction and subsequent loss of remission in patients with moderately active rheumatoid arthritis (RA) who received full-dose combination etanercept plus methotrexate induction ...
Josef S. Smolen +4 more
doaj +2 more sources