Results 41 to 50 of about 3,279 (166)

Transposase‐Assisted Donor Tethering Boosts Large‐Fragment HDR in Plants

Advanced Science, Volume 13, Issue 43, 3 August 2026.
A transposase‐assisted donor tethering strategy is developed to enhance homology‐directed repair in plants. By recruiting donor DNA to double‐strand breaks and synergizing with repair pathway reprogramming and transcription‐coupled donor design, this system markedly improves large‐fragment targeted insertion efficiency, providing a robust platform for ...
Sha Wei, Kai Zhang, Shuke Deng, Jinjie Chen, Xiaomei Huang, Jingfei Guo, Yuqing Wu, Yingjie Guo, Zhen Liang   +8 more
wiley   +1 more source

Predictor of the Simplified Disease Activity Index 50 (SDAI 50) at Month 3 of bDMARD Treatment in Patients with Long-Established Rheumatoid Arthritis

, 2017
Objectives:The Simplified Disease Activity Index (SDAI) 50 has good agreement with European League Against Rheumatism (EULAR) response measures for early Rheumatoid Arthritis (RA). There have been reports on early RA, but not on long-established RA.
Mayu Saito, Hidekazu Furuya, Tsuyoshi Kasama, Ryo Yanai, Yusuke Miwa   +4 more
core   +1 more source

Validación del inventario de ansiedad dental versión corta (SDAI) para su uso en pacientes mexicanos. [PDF]

, 2018
Es importante contar con herramientas para evaluar la ansiedad en procedimientos dentales en pacientes adultos usando instrumentos breves, confiables y válidos para este fin, como el Inventario de Ansiedad Dental versión corta (SDAI), por lo que es ...
Cárdenas Caraza, Laura Aracely; Universidad de Monterrey., Cázares de León, Francisco; Universidad de Monterrey.   +1 more
core   +1 more source

Impact of early age at menopause on disease outcomes in postmenopausal women with rheumatoid arthritis: a large observational cohort study of Korean patients with rheumatoid arthritis

RMD Open, 2023
Objectives To assess the differences in clinical outcomes between patients with rheumatoid arthritis (RA) with early menopause (EM) (<45 years) and usual menopause (UM) (≥45 years) and to identify the impact of EM on longitudinal changes in RA ...
Yun Jong Lee, You-Jung Ha, Eun Ha Kang, Eun Hye Park   +3 more
doaj   +1 more source

PD‐1hiCXCR5−CD4+T Peripheral Helper Cells Were Enriched and Potentially Predicted Clinical Response to Etanercept Therapy in Rheumatoid Arthritis

MedComm, Volume 7, Issue 8, August 2026.
This study investigated the role of PD‐1hiCXCR5−CD4+ T peripheral helper (Tph) cells in rheumatoid arthritis (RA). Tph cells were increased in the peripheral blood of RA patients and associated with disease activity. Baseline Tph cell levels were linked to the response to etanercept therapy.
Haojie Xu, Wanki Ho, Lulu Cao, Dongdong Fu, Yun Li, Feng Sun, Xi Xu, Zhanguo Li, Ru Li, Hua Ye, Huaqun Zhu   +10 more
wiley   +1 more source

Factors associated with discrepancies in disease activity as assessed by SDAI and RAPID3 in patients with rheumatoid arthritis: Data from a multicentre observational study (T-FLAG) [PDF]

Objectives: The present study aimed to examine discrepancies between assessments based on Routine Assessment of Patient Index Data 3 (RAPID3) and Simple Disease Activity Index (SDAI) in rheumatoid arthritis (RA) patients with controlled disease activity.
Terabe, Kenya, Ishikawa, Hisato, Imagama, Shiro, Sugiura, Takaya, Takahashi, Nobunori, Hasegawa, Junya, Ohno, Yusuke, Sato, Ryo, Suzuki, Mochihito, Sobue, Yasumori, Asai, Shuji, Ohashi, Yoshifumi, Kosugiyama, Hironobu   +12 more
core   +2 more sources

Predictors of remission with etanercept-methotrexate induction therapy and loss of remission with etanercept maintenance, reduction, or withdrawal in moderately active rheumatoid arthritis: results of the PRESERVE trial

Arthritis Research & Therapy, 2018
Background The aim was to analyze characteristics that predict remission induction and subsequent loss of remission in patients with moderately active rheumatoid arthritis (RA) who received full-dose combination etanercept plus methotrexate induction ...
Josef S. Smolen, Annette Szumski, Andrew S. Koenig, Thomas V. Jones, Lisa Marshall   +4 more
doaj   +1 more source

Anti‐Modified Protein Antibodies in Rheumatoid Arthritis: Pathogenic, Protective, or Passive Bystander?

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT The presence of anti‐modified protein antibodies (AMPA) is a hallmark of rheumatoid arthritis (RA). AMPA recognize post‐translationally modified proteins and are cross‐reactive. AMPA include anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA).
Amber‐Sarai F. L. Stalman, Diane van der Woude   +1 more
wiley   +1 more source

2024 Update of the Asia‐Pacific League of Associations for Rheumatology (APLAR) Recommendations for Rheumatoid Arthritis Management

International Journal of Rheumatic Diseases, Volume 29, Issue 7, July 2026.
ABSTRACT Aim To update the Asia‐Pacific League of Associations for Rheumatology (APLAR) treatment recommendations for rheumatoid arthritis (RA) by incorporating new evidence and reassessing the validity of previous guidance: Methods A literature search for relevant publications from January 2018 to August 2023 was conducted, supplemented by earlier ...
Kunihiro Yamaoka, Zhanguo Li, Khin Thin Zar Myo Aung, Paul Bird, Manisha Bhochhibhoya, Minhaj Rahim Choudhury, Debashish Danda, Tsolmon Darisuren, Rudy Hidayat, Nguyen Van Hung, Yuko Kaneko, Wanruchada Katchamart, Manjari Lahiri, Chin Teck Ng, Babur Salim, Keshav Raj Sigdel, Shereen Ch'ng Suyin, Tsutomu Takeuchi, Galymzhan Togizbayev, Evan Vista, Sandini Wijeweera, Chuanhui Xu, Chak Sing Lau   +22 more
wiley   +1 more source

Mesenchymal stromal cell therapy for feline chronic gingivostomatitis: Long term experience

Frontiers in Veterinary Science, 2023
IntroductionMesenchymal stromal cells (MSC) therapy has emerged as a potential treatment option for refractory FCGS. However, there is a lack of long-term data on the use of MSC therapy in cats.
Maria Soltero-Rivera, Sterling Hart, Andrew Blandino, Natalia Vapniarsky, Natalia Vapniarsky, Boaz Arzi, Boaz Arzi   +6 more
doaj   +1 more source