Results 61 to 70 of about 3,279 (166)

Aiming for SDAI remission versus low disease activity at 1 year after inclusion in ESPOIR cohort is associated with better 3-year structural outcomes

, 2014
International audienceOBJECTIVES: Using data for patients with early rheumatoid arthritis (RA) from the ESPOIR cohort, we aimed to evaluate the impact of remission versus low disease activity (LDA) by the Simple Disease Activity Index (SDAI) at 1 year on
Nigon, Delphine, Jamard, Bénédicte, Guernec, Gregory, Constantin, Arnaud, Ruyssen-Witrand, Adeline, Rat, Anne-Christine, Vittecoq, Olivier, Cantagrel, Alain, Tobon, Gabriel   +8 more
core   +1 more source

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 78, Issue 4, Page 809-820, April 2026.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis III, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy J. Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

HUPI and DAS28 discriminate low-moderate and moderate-high disease activity better than SDAI and CDAI.

, 2016
Receiver operating curves were plot using the “roctab” command of STATA, with the option graph. Data obtained from the PEARL cohort. The best cut-off point to discriminate between moderate and high disease activity was 9 (Table 3).
Ana M. Ortiz (189947), Esther Toledano (3107682), Isidoro González-Álvaro (118679), Isabel Castrejón (3107679), Santos Castañeda (118673), Alberto García-Vadillo (3107685), Loreto Carmona (63759)   +6 more
core   +1 more source

Response criteria for rheumatoid arthritis in clinical practice - how useful are they? [PDF]

, 2005
Objective: To compare the performance of the American College of Rheumatology (ACR), European League Against Rheumatism (EULAR), and simple disease activity index (SDAI) response criteria for rheumatoid arthritis at the individual level in an ...
Geborek, Pierre, Saxne, Tore, Gülfe, Anders   +2 more
core   +1 more source

Insights Into Late‐Onset Rheumatoid Arthritis (LORA): Characteristics (Clinical and Imaging), Comorbidities, and Therapeutic Targets

Geriatrics &Gerontology International, Volume 26, Issue 2, February 2026.
The main features of late‐onset rheumatoid arthritis (LORA), manifesting after age 65, are acute onset, higher disease activity, systemic involvement, and less presence of autoantibodies. Management requires individualized strategies, balancing aggressive treat‐to‐target therapy in robust patients with frailty‐focused approaches to prevent geriatric ...
Fausto Salaffi, Marina Carotti, Sonia Farah, Francesca Bandinelli, Luca Ceccarelli, Andrea Di Matteo, Marco Di Carlo   +6 more
wiley   +1 more source

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

Receiver operating curves (ROC) for HUPI, SDAI and DAS28 to discriminate remission.

, 2016
A) Remission defined by rheumatologist consensus in PEARL population. B) Remission defined by Pinals criteria in EMECAR population. C) Remission defined by ACR/EULAR boolean criteria in PEARL population.
Ana M. Ortiz (189947), Esther Toledano (3107682), Isidoro González-Álvaro (118679), Isabel Castrejón (3107679), Santos Castañeda (118673), Alberto García-Vadillo (3107685), Loreto Carmona (63759)   +6 more
core   +1 more source

Serum BAFF is associated with clinical background and simplified disease activity index (SDAI) in patients with rheumatoid arthritis [PDF]

【Objectives】The B- cell activating factor belonging to TNF family (BAFF) might play a pathogenic role in rheumatoid arthritis (RA) because it has been reported that BAFF levels increases in RA serum, and anti -BAFF mAb ameliorates RA activity.
三村, 俊英, 1855, 1854, 1861, Nakajima, Kyoichi, 1860, 進藤, 靖史, 神津, 教倫, Mimura, Toshihide, Kozu, Noritsune, 1859, 1858, 1857, 中嶋, 京一, 1856, Shindo, Yasufumi   +15 more
core   +1 more source

Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis

Rheumatology and Therapy
Introduction Although the efficacy of tumor necrosis factor inhibitors (TNFi) is reduced in patients with rheumatoid factor (RF)-high rheumatoid arthritis (RA), certolizumab pegol (CZP), lacking the Fc portion, may not be affected.
Atsushi Nagayasu, Yusuke Miyazaki, Koshiro Sonomoto, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Hiroaki Tanaka, Yasuyuki Todoroki, Masanobu Ueno, Takafumi Aritomi, Yuya Fujita, Hidenori Sakai, Katsunori Suzuki, Shingo Nakayamada, Yoshiya Tanaka   +14 more
doaj   +1 more source

Czech validation of the Attitudes to Inclusion Scale and the Intention to Teach in Inclusive Classroom Scale among primary school teachers

Journal of Research in Special Educational Needs, Volume 25, Issue 3, Page 485-499, July 2025.
Abstract The Attitudes to Inclusion Scale (AIS) and the Intention to Teach in Inclusive Classroom Scale (ITICS) are instruments widely used internationally for researching teachers' attitudes and intentions towards inclusive education (IE). This study presents information on psychometric analysis of the AIS and ITICS as well as their functioning in the
Jakub Pivarč
wiley   +1 more source