Results 71 to 80 of about 3,460 (162)

Influence of Rheumatoid Factors on the Efficacy of TNF Inhibitor Therapy in Patients with Rheumatoid Arthritis

Rheumatology and Therapy
Introduction Although the efficacy of tumor necrosis factor inhibitors (TNFi) is reduced in patients with rheumatoid factor (RF)-high rheumatoid arthritis (RA), certolizumab pegol (CZP), lacking the Fc portion, may not be affected.
Atsushi Nagayasu, Yusuke Miyazaki, Koshiro Sonomoto, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Hiroaki Tanaka, Yasuyuki Todoroki, Masanobu Ueno, Takafumi Aritomi, Yuya Fujita, Hidenori Sakai, Katsunori Suzuki, Shingo Nakayamada, Yoshiya Tanaka   +14 more
doaj   +1 more source

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao, Qinyang Zhang, Yu Jiang, Dagang Tang, Xiao Qu, Jun Zhang, Yi Chen, Weixia Duan, Tao Li, Zhengwei Cai, Yanran Huang, Xiaoji Luo   +11 more
wiley   +1 more source

HUPI and DAS28 discriminate low-moderate and moderate-high disease activity better than SDAI and CDAI.

, 2016
Receiver operating curves were plot using the “roctab” command of STATA, with the option graph. Data obtained from the PEARL cohort. The best cut-off point to discriminate between moderate and high disease activity was 9 (Table 3).
Ana M. Ortiz (189947), Esther Toledano (3107682), Isidoro González-Álvaro (118679), Isabel Castrejón (3107679), Santos Castañeda (118673), Alberto García-Vadillo (3107685), Loreto Carmona (63759)   +6 more
core   +1 more source

Relapse in rheumatoid arthritis patients undergoing dose reduction and withdrawal of biologics: are predictable factors more relevant than predictive parameters? An observational prospective real-life study

BMJ Open, 2019
Objective To determine predictive/predictable factors of relapse in rheumatoid arthritis (RA) patients undergoing biologic Disease-Modifying Anti-Rheumatic Drugs (bDMARDs) dose reduction/discontinuation.Patients and methods RA patients receiving the same
Sophie Pouplin, Olivier Vittecoq, Marie Kozyreff, Julia Nicolau, Pascal Rottenberg, Nicolas Sens, Thierry Lequerre, Gilles Avenel   +7 more
doaj   +1 more source

''Evaluating disease activity in rheumatoid arthritis: Which composite index is best? A systematic literature analysis of studies comparing the psychometric properties of the DAS, DAS28, SDAI and CDAI''

, 2012
Gaujoux-Viala, Cecile | Mouterde, Gael | Baillet, Athan | Claudepierre, Pascal | Fautrel, Bruno | Le Loet, Xavier | Maillefert, Jean-FrancisInternational audience''Objectives: To evaluate and compare four composite indices for assessing the activity of ...
Maillefert, Jean-Francis, Gaujoux-Viala, Cecile, Fautrel, Bruno, Xavier Le, Loet, Mouterde, Gael, Pascal Claudepierre, Bruno Fautrel, Jean-Francis Maillefert, Baillet, Athan, Athan Baillet, Claudepierre, Pascal, Gaël Mouterde, Xavier Le Loët, Cécile Gaujoux-Viala, Le Loët, Xavier   +14 more
core   +1 more source

Reviewing Treatment Trends and Effectiveness of Medication for Patients with Rheumatoid Arthritis Throughout 15 Years Under the Treat-to-Target Strategy in Real-World Practice in Japan

Rheumato
Objectives: The evidence for treating rheumatoid arthritis (RA) with a treat-to-target (T2T) approach was examined for clinical outcomes. Methods: Since August 2010, RA treatment has implemented the T2T strategy, aiming to achieve a simplified disease ...
Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa   +2 more
doaj   +1 more source

Correlação dos índices de atividade da artrite reumatoide (Disease Activity Score 28 medidos com VHS, PCR, Simplified Disease Activity Index e Clinical Disease Activity Index) e concordância dos estados de atividade da doença com vários pontos de corte numa população do nordeste brasileiro

Revista Brasileira de Reumatologia, 2015
Resumo Introdução: O Disease Activity Score 28 (DAS28) e versões têm sido usados para medir atividade da artrite reumatoide (AR), mas não existe consenso sobre qual é o melhor.
Marta Maria das Chagas Medeiros, Brenda Maria Gurgel Barreto de Oliveira, João Victor Medeiros de Cerqueira, Raquel Telles de Souza Quixadá, Ídila Mont’Alverne Xavier de Oliveira   +4 more
doaj   +1 more source

Real World Experience of Disease Activity in Patients With Rheumatoid Arthritis and Response to Treatment With Varios Biologic DMARDs

Frontiers in Pharmacology, 2018
The current study investigate the disease activity and effectiveness of treatment in patients with RA on biological disease modifying antirheumatic drugs (bDMARDs) in combination with a conventional synthetic DMARD (csDMARD) and determine whether or not ...
Vladimira Boyadzhieva, Nikolay Stoilov, Mariana Ivanova, Guenka Petrova, Rumen Stoilov   +4 more
doaj   +1 more source

Common Evaluations of Disease Activity in Rheumatoid Arthritis Reach Discordant Classifications across Different Populations

Frontiers in Medicine, 2018
ObjectivesThe classification of disease activity states in rheumatoid arthritis (RA) can be achieved through disease activity indices, such as the Disease Activity Score in 28 joints erythrocyte sedimentation rate (DAS28-ESR), the Simplified Disease ...
Helena Canhão, Helena Canhão, Ana Maria Rodrigues, Maria João Gregório, Sara S. Dias, José António Melo Gomes, Maria José Santos, Maria José Santos, Augusto Faustino, José António Costa, Cornelia Allaart, Emilia Gvozdenović, Desirée van der Heijde, Pedro Machado, Jaime C. Branco, Jaime C. Branco, João Eurico Fonseca, João Eurico Fonseca, José António Silva   +18 more
doaj   +1 more source

Response criteria for rheumatoid arthritis in clinical practice - how useful are they? [PDF]

, 2005
Objective: To compare the performance of the American College of Rheumatology (ACR), European League Against Rheumatism (EULAR), and simple disease activity index (SDAI) response criteria for rheumatoid arthritis at the individual level in an ...
Geborek, Pierre, Saxne, Tore, Gülfe, Anders, A Gulfe, Geborek, Pierre,, Saxne, Tore,, Gülfe, Anders,, Lund University.   +7 more
core   +1 more source