Beyond the Barrier: Epithelial Cells as Immune Sentinels in the Female Genital Tract
ABSTRACT Epithelial cells (ECs) of the female genital tract (FGT) serve as an essential barrier and the first line of defense against sexually transmitted pathogens. Beyond providing a physical barrier, these cells actively contribute to immune responses through pathogen recognition, cytokine release, and modulation of adaptive immune responses ...
Lauren Jirik +3 more
wiley +1 more source
Portulaca oleracea L seed extracts counteract diabetic nephropathy through SDF-1/IL10/PPARγ-mediated tuning of keap1/Nrf2 and NF-κB transcription in Sprague Dawley rats. [PDF]
Aziz WM +5 more
europepmc +1 more source
ABSTRACT The Natura 2000 (N2K)—Europe's network of protected areas—is a key conservation instrument, but its effectiveness is challenged by climate change. We surveyed 382 N2K managers to investigate their perceptions of climate change and related site adaptation strategies.
Giorgio Zavattoni +9 more
wiley +1 more source
Transcriptomics and Proteomics Reveal That TLPW Acupuncture Ameliorates Proteinuria in Diabetic Kidney Disease Model Rats by Suppressing Epithelial-to-Mesenchymal Transition via the DPP4/SDF-1α/TGF-β/Smad Signalling Axis. [PDF]
Ji Y +7 more
europepmc +1 more source
Summary Background Injury of the superficial digital flexor tendon (SDFT) branch is uncommon and the response to different treatments has not been reported. Objectives The aim of this study was to describe the clinical presentation, diagnostic features, treatment methods, and outcome of horses diagnosed with SDFT branch injuries.
P. Spiesshofer +3 more
wiley +1 more source
Overexpression of Nrf2 in bone marrow mesenchymal stem cells promotes B-cell acute lymphoblastic leukemia cells invasion and extramedullary organ infiltration through stimulation of the SDF-1/CXCR4 axis. [PDF]
Zheng L +11 more
europepmc +1 more source
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