Results 281 to 290 of about 27,322,199 (337)
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The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry
Nature, 1996Michael Farzan +2 more
exaly +2 more sources
G-CSF induces stem cell mobilization by decreasing bone marrow SDF-1 and up-regulating CXCR4
Nature Immunology, 2002isabelle Petit +2 more
exaly +2 more sources
ACS Applied Materials and Interfaces, 2021
Existing local drug delivery systems for periodontitis suffer from poor antibacterial effect and unsatisfied periodontal regeneration. In this study, a smart gingipain-responsive hydrogel (PEGPD@SDF-1) was synthesized as an environmentally sensitive ...
Shiyue Liu +5 more
semanticscholar +1 more source
Existing local drug delivery systems for periodontitis suffer from poor antibacterial effect and unsatisfied periodontal regeneration. In this study, a smart gingipain-responsive hydrogel (PEGPD@SDF-1) was synthesized as an environmentally sensitive ...
Shiyue Liu +5 more
semanticscholar +1 more source
Effect of genipin crosslinked chitosan scaffolds containing SDF-1 on wound healing in a rat model.
Materials Science and Engineering C: Materials for Biological Applications, 2020Prolonged healing is a severe problem for elderly and diabetic patients. Impaired angiogenesis, stem cell differentiation, and migration have been shown to delay wound healing.
C. Yao +4 more
semanticscholar +1 more source
Bone, 2019
Crosstalk between subchondral bone and articular cartilage is considered a central feature of osteoarthritis (OA) initiation and progression, but its underlying molecular mechanism remains elusive.
Hanjun Qin +12 more
semanticscholar +1 more source
Crosstalk between subchondral bone and articular cartilage is considered a central feature of osteoarthritis (OA) initiation and progression, but its underlying molecular mechanism remains elusive.
Hanjun Qin +12 more
semanticscholar +1 more source
SDF-1 keeps HSC quiescent at home
Blood, 2011In this issue of Blood , Tzeng et al report on the generation of adult, conditional SDF-1–deficient mice in which HSC quiescence and endosteal niche localization are impaired.[1][1] The chemokine stromal cell–derived factor 1 (SDF-1; CXCL12), and its major receptor CXCR4, regulate many ...
Tomer, Itkin, Tsvee, Lapidot
openaire +2 more sources
Functional Characterization of SDF-1 Proximal Promoter
Journal of Molecular Biology, 2005Stromal-cell derived factor 1 (SDF1) is a CXC chemokine that binds and signals through the CXCR4 receptor, playing an essential role in embryonic B lymphopoiesis, myelopoiesis and organogenesis. The CXCR4/SDF1 pathway is associated with several pathologies.
Carelia, García-Moruja +9 more
openaire +2 more sources
Cancer Letters, 2011
Bone marrow metastasis is frequently observed in patients with high-risk neuroblastoma. Mesenchymal stromal cells (MSCs) in bone marrow may enhance tumor metastasis through secreting stromal cell-derived factor-1 (SDF-1). Here we investigated neuroblastoma cell behaviors under the influence of MSCs and explored the function of SDF-1 signaling during ...
Deng, R +4 more
openaire +4 more sources
Bone marrow metastasis is frequently observed in patients with high-risk neuroblastoma. Mesenchymal stromal cells (MSCs) in bone marrow may enhance tumor metastasis through secreting stromal cell-derived factor-1 (SDF-1). Here we investigated neuroblastoma cell behaviors under the influence of MSCs and explored the function of SDF-1 signaling during ...
Deng, R +4 more
openaire +4 more sources
SDF-1 Signaling in Myeloid Malignancies,
Blood, 2011Abstract Abstract 3824 The factor SDF-1 (stromal derived factor-1) was identified as an important chemoattractant factor produced by bone marrow cells. SDF-1 acts on its receptor CXCR4 and plays primordial function in migration, retention and development of hematopoietic progenitors in bone marrow.
Rita de Cassia Carvalho Melo +5 more
openaire +1 more source