Results 51 to 60 of about 29,746,039 (283)

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Quantitative Phosphoproteomics of CXCL12 (SDF-1) Signaling

PLoS ONE, 2011
CXCL12 (SDF-1) is a chemokine that binds to and signals through the seven transmembrane receptor CXCR4. The CXCL12/CXCR4 signaling axis has been implicated in both cancer metastases and human immunodeficiency virus type 1 (HIV-1) infection and a more complete understanding of CXCL12/CXCR4 signaling pathways may support efforts to develop therapeutics ...
Jason A Wojcechowskyj, Jessica Y Lee, Steven H Seeholzer, Robert W Doms   +3 more
openaire   +4 more sources

Directional Latent Hybridization: Beyond Random Noise in Physics‐Informed Generative Inverse Design of Nonlinear Metamaterials

Advanced Materials Technologies, EarlyView.
A physics‐informed generative framework introduces Directional Latent Hybridization (DLH) for the deterministic inverse design of nonlinear metamaterials. By hybridizing dominant traits from parent geometries in the latent space, DLH overcomes the instabilities of stochastic models to ensure high structural precision at high densities.
Semin Ahn, Jun Young Choi, Sung‐Hoon Ahn   +2 more
wiley   +1 more source

SDF-1α gene-activated collagen scaffold drives functional differentiation of human Schwann cells for wound healing applications

, 2022
Enhancing angiogenesis is the prime target of current biomaterial-based wound healing strategies. However, these approaches largely overlook the angiogenic role of the cells of the nervous system. Therefore, we explored the role of a collagen-chondroitin
Ashang L. Laiva (12595780), Michael Keogh (12596932), Fergal O'Brien (7895480)   +2 more
core   +3 more sources

Stromal Cell-Derived Factor-1 Promotes Cell Migration, Tumor Growth of Colorectal Metastasis

Neoplasia: An International Journal for Oncology Research, 2007
In a mouse model of established extrahepatic colorectal metastasis, we analyzed whether stromal cellderived factor (SDF) 1 stimulates tumor cell migration in vitro, angiogenesis, tumor growth in vivo.
Otto Kollmar, Kathrin Rupertus, Claudia Scheuer, Bastian Junker, Bettina Tilton, Martin K. Schilling, Michael D. Menger   +6 more
doaj   +1 more source

Why not use SDF‐ rather than beta models in performance measurement [PDF]

, 2012
This paper analyzes performance measurement based on stochastic discount factors, compared to beta modelstraditionally used in computing funds’ (Jensen) alphas. From a theoretical point of view, standard alphas sufferfrom several limitations.
Zimmermann, Heinz, Gusset, Jonas
core  

Study on the Promotion of hADSCs Migration and Chemotaxis by SDF-1

Asia-Pacific Journal of Ophthalmology, 2023
The purpose of this study was to investigate the chemotaxis effect of stromal cell-derived factor-1 (SDF-1) on human adipose-derived stem cells (hADSCs).A lentivirus vector with the enhanced green fluorescent protein gene was constructed and transfected to hADSCs.
Chen, Jin, Guoxing, Xu
openaire   +2 more sources

Phase Diagrams and Piezoelectric Properties of Wurtzite Al1−x−yScxGdyN Heterostructural Alloys

Advanced Science, EarlyView.
This study demonstrates ferroelectricity and piezoelectric properties improvement of quaternary wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films, guided by density functional theory calculations. Wurtzite Al1−x−yScxGdyN${\rm Al}_{1-x-y}{\rm Sc}_x{\rm Gd}_y{\rm N}$ films have a high optical bandgap, enhanced piezoelectric ...
Julia L. Martin, Cheng‐Wei Lee, Nate S.P. Bernstein, Thi Nguyen, Ande Bryan, Eli Cooper, John S. Mangum, Sage R. Bauers, Andriy Zakutayev, Keisuke Yazawa, Prashun Gorai, Rebecca W. Smaha   +11 more
wiley   +1 more source

The Potential of EMSA Eritin to Modulate T Cells (CD4+ and CD8+) in Balb/C Mice Model of Diabetes Mellitus

Journal of Experimental Life Science, 2015
EMSA Eritin is a medicinal polyherbal contains with soy bean, coconut water and red rice extract. In several studies of this individual components have proven the potential to modulate lymphocyte cells that indirectly lowering blood glucose levels in ...
Ade MC Rohie, Muhaimin Rifa'i
doaj   +1 more source

SDF-1 directs megakaryocyte relocation

Blood, 2014
In this issue of Blood, Niswander et al answer the questions: (1) Does stromal cell-derived factor 1 (SDF-1) direct megakaryocyte spatial distribution in the bone marrow? and (2) What effect does local SDF-1 concentration have on platelet output?1 If Jose Arcadio Buendia in One Hundred Years of Solitude2 had followed SDF-1, as megakaryocytes do ...
openaire   +3 more sources