Results 41 to 50 of about 29,746,039 (283)

CXC chemokine ligand 12/Stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1

open access: yesJournal of Biomedical Science, 2012
Background The CXC chemokine ligand 12 (CXCL12)/stromal cell-derived factor-1 (SDF-1) and CXC receptor 4 (CXCR4) axis is involved in human colorectal cancer (CRC) carcinogenesis and can promote the progression of CRC.
Tung Shui-Yi   +7 more
doaj   +1 more source

Phosphoric Acid Etch Partially Restores the Initial Bond Strength of Composite to Silver Diamine Fluoride–Treated Enamel Using Universal Adhesives

open access: yesDentistry Journal, 2023
Background: Restoring bonding composite to silver diamine fluoride (SDF)-treated enamel is challenging. This study investigates if phosphoric acid etch restores composite bond strength to SDF-treated enamel using universal adhesives. Methods: Twenty-four
Zaher Jabbour   +3 more
doaj   +1 more source

Sdf-1alpha up-Regulates Interleukin-6 through Cxcr4, Pi3k/Akt, Erk, and Nf -Kappab-Dependent Pathway in Microglia

open access: yes, 2011
Stromal cell-derived factor-1 (SDF-1), also known as CXCL12, and its receptor CXC chemokine receptor 4 (CXCR4) express in various kinds of cells in central nervous system. The SDF -1/CXCR4 signaling pathway is regulated by diverse biological effects. SDF-
LU, DAH-YUU;TANG, CHIH-HSIN;YEH, WEI-LAN;WONG, KAR-LOK;LIN, CHIH-PENG;CHEN, YI-HUNG;LAI, CHIH-HO;CHEN, YUH-FUNG;LEUNG, YUK-MAN;FU, WEN- MEI;FU, WEN-MEI   +1 more
core   +1 more source

Functional diversity of SDF-1 splicing variants [PDF]

open access: yesCell Adhesion & Migration, 2009
SDF-1 is ubiquitously expressed in vertebrate tissues in a constitutive manner. It performs an essential role in cell migration and proliferation as well as participates in tissue-specific physiological processes such as neuromodulation. It is also involved in many pathological processes including: HIV infection, metastatic malignancy, chronic ...
openaire   +2 more sources

Anti-Fibrotic Effect of SDF-1β Overexpression in Bleomycin-Injured Rat Lung [PDF]

open access: yes, 2022
Rational: Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease and is associated with high mortality due to a lack of effective treatment.
Lars Knudsen   +18 more
core   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Enhanced osteogenic capacity of octacalcium phosphate involving adsorption of stromal-derived factor-1 in a standardized defect of a rat femur

open access: yesJournal of Materials Science: Materials in Medicine
This study investigated whether octacalcium phosphate (OCP) enhances bone regeneration through its synergistic effect with stromal-derived factor-1 (SDF-1). Recombinant SDF-1 (0.5–5.0 μg) was combined with OCP granules through lyophilization.
Ryuichi Kanabuchi   +8 more
doaj   +1 more source

Engineered Small Extra-Cellular Vesicles for Endogenous Mesenchymal Stem Cells Recruitment and in situ Periodontal Tissue Regeneration

open access: yesDentistry Review
OBJECTIVES: Exo released by immune-regulatory dendritic cells (regDCs) have been used as an effective nanodelivery system for the reprogramming of immune response at inflammatory bone defects in mice.
Cathy Tran, Ranya Elsayed, PhD MBA
doaj   +1 more source

Effects of SDF-1/CXCR7 on the Migration, Invasion and Epithelial-Mesenchymal Transition of Gastric Cancer Cells

open access: yesFrontiers in Genetics, 2021
We found that SDF-1/CXCR7 axis played an important role in the growth and proliferation of gastric cancer in the previous studies. The objectives of this study were to explore the effects of SDF-1/CXCR7 on the metastatic ability of gastric cancer cells ...
Ameng Shi   +4 more
doaj   +1 more source

SDF-1/CXCR4 signalling is involved in blood vessel growth and remodelling by intussusception. [PDF]

open access: yes, 2019
The precise mechanisms of SDF-1 (CXCL12) in angiogenesis are not fully elucidated. Recently, we showed that Notch inhibition induces extensive intussusceptive angiogenesis by recruitment of mononuclear cells and it was associated with increased levels of
Vladislav Volarevic   +18 more
core   +2 more sources

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