Results 31 to 40 of about 27,322,199 (337)

Chemokine-induced secretion of gelatinase B in primary human monocytes [PDF]

open access: yes, 2001
Chemokines help control normal leukocyte trafficking as well as their infiltration into tissues during acute and chronic inflammation. Matrix metalloproteinases (MMPs) help support the extravasation and infiltration of leukocytes through limited ...
Brew K.   +7 more
core   +1 more source

SDF-1 and PDGF enhance [alpha]v[beta]5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines [PDF]

open access: yes, 2009
CD23 acts through the [alpha]v[beta]5 integrin to promote growth of human pre-B cell lines in an adhesion-independent manner. [alpha]v[beta]5 is expressed on normal B-cell precursors in the bone marrow.
Acharya, M.   +3 more
core   +2 more sources

A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor

open access: yesViruses, 2019
CXC chemokine receptor 4 (CXCR4) is a co-receptor for HIV-1 entry into target cells. Its natural ligand, the chemokine SDF-1, inhibits viral entry mediated by this receptor. However, the broad expression pattern of CXCR4 and its critical roles in various
Suiyi Tan   +13 more
doaj   +1 more source

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development

open access: yesJournal of Experimental Medicine, 2006
The chemokine stromal cell–derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac and neuronal development, stem cell motility, neovascularization, angiogenesis, apoptosis, and ...
J. Burns   +14 more
semanticscholar   +1 more source

SDF-1/CXCL12 modulates mitochondrial respiration of immature blood cells in a bi-phasic manner [PDF]

open access: yes, 2016
SDF-1/CXCL12 is a potent chemokine required for the homing and engraftment of hematopoietic stem and progenitor cells. Previous data from our group has shown that in an SDF-1/CXCL12 transgenic mouse model, lineage(-) Sca-1(+) c-Kit(+) (LSK) bone marrow ...
Broxmeyer, Hal, Messina-Graham, Steven
core   +1 more source

SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

open access: yesStem Cell Research & Therapy, 2023
Background Islet transplantation is used therapeutically in a minority of patients with type 1 diabetes (T1D). However, successful outcomes are hampered by early islet β-cell loss caused by immune rejection and autoimmunity.
Mingxing Sui   +7 more
doaj   +1 more source

Dipeptidylpeptidase IV (CD26) defines leukemic stem cells (LSC) in chronic myeloid leukemia [PDF]

open access: yes, 2014
Chronic myeloid leukemia (CML) is a stem cell (SC) neoplasm characterized by the BCR/ABL1 oncogene. Although mechanisms of BCR/ABL1-induced transformation are well-defined, little is known about effector-molecules contributing to malignant expansion and ...
Bilban, Martin   +15 more
core   +1 more source

Histological Examination of Engineered Mesenchymal Stem Cells Improve Bladder Function in Rat

open access: yesKorean Journal of Clinical Laboratory Science, 2020
This study was undertaken to examine the effects and to investigate the relevant mechanisms of overexpressing stromal cell-derived factor-1 (SDF-1) produced by engineered mesenchymal stem cells, in a neurogenic bladder (NB) rat model. Sprague-Dawley (SD)
Eun Kyung Cho, Seung Hwan Jeon
doaj   +1 more source

Deletion of SDF-1 or CXCR4 regulates platelet activation linked to glucose metabolism and mitochondrial respiratory reserve

open access: yesPlatelets, 2022
Stromal cell-derived factor 1 (SDF-1, also known as CXCL12) and its receptor CXCR4 have shown to play a role in the homing and engraftment of hematopoietic stem and progenitor cells.
Yi Li   +5 more
doaj   +1 more source

A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)

open access: yesJournal of Experimental Medicine, 1996
Chemotactic factors are postulated to direct emigration of lymphocytes from the blood stream into sites of inflammation. Members of a family of chemotactic cytokines, termed chemokines, have been shown to attract lymphocytes but efficacy, i.e., the ...
C. Bleul   +4 more
semanticscholar   +1 more source

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