Results 31 to 40 of about 29,746,039 (283)

SOCS3 inhibits the mesenchymal stromal cell secretory factor SDF-1-mediated improvement of islet function in non-obese diabetic mice

open access: yesStem Cell Research & Therapy, 2023
Background Islet transplantation is used therapeutically in a minority of patients with type 1 diabetes (T1D). However, successful outcomes are hampered by early islet β-cell loss caused by immune rejection and autoimmunity.
Mingxing Sui   +7 more
doaj   +1 more source

SDF-1α gene-activated collagen scaffold enhances provasculogenic response in a coculture of human endothelial cells with human adipose-derived stromal cells

open access: yes, 2022
Novel biomaterials can be used to provide a better environment for cross talk between vessel forming endothelial cells and wound healing instructor stem cells for tissue regeneration.
Michael Keogh (12596932)   +2 more
core   +3 more sources

Continuous Delivery of Stromal Cell-Derived Factor-1 from Alginate Scaffolds Accelerates Wound Healing

open access: yesCell Transplantation, 2010
Proper wound diagnosis and management is an increasingly important clinical challenge and is a large and growing unmet need. Pressure ulcers, hard-to-heal wounds, and problematic surgical incisions are emerging at increasing frequencies.
Sina Y. Rabbany   +6 more
doaj   +1 more source

The role of the chemokine receptor CXCR4 in oral squamous cell carcinoma metastasis [PDF]

open access: yes, 2010
PhDOral Squamous Cell Carcinoma (OSCC) is the sixth most common cancer worldwide. The greatest cause of mortality and surgical morbidity is due to the common spread of tumour cells from the primary lesion to the lymph nodes of the neck. This pathway is
Collier, Jonathan Marc
core   +4 more sources

Effect of integrin α5β1 inhibition on SDF-l/CXCR4- mediated choroidal neovascularization [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To investigate the roles of integrins in choroidal neovascularization (CNV) and their associations with the stromal cell-derived factor-1 (SDF-1)/CXCR4 axis. METHODS: CNV lesions were induced in mice using laser photocoagulation.
Yang Lyu   +5 more
doaj   +1 more source

“The potential role of CXCR4 and SDF-1 as indicators of tumor aggressiviness in patients with conventional papillary thyroid carcinoma” [PDF]

open access: yes, 2008
Background: Functional chemokine receptors are expressed in many malignant tumors, including papillary thyroid carcinoma (PTC). These receptors promote tumor growth and metastasis in response to endogenous chemokines.
Pagano, Loredana
core   +1 more source

SDF-1 preconditioned HPC scaffolds mobilize cartilage-derived progenitors and stimulate meniscal fibrocartilage repair in human explant tissue culture

open access: yes, 2019
Purpose: The purpose of this study was to characterize the influence of SDF-1 on cell migration/adhesion and temporal gene expression of human cartilage mesenchymal progenitor cells (C-PCs); and to utilize SDF-1 conditioned mesenchymal progenitors to ...
Jake Newberry (7890896)   +6 more
core   +1 more source

SDF1 Gene Variation Is Associated with Circulating SDF1 alpha Level and Endothelial Progenitor Cell Number-The Bruneck Study [PDF]

open access: yes, 2008
BACKGROUND: Stromal cell-derived factor-1 (SDF1) and its receptor CXC chemokine receptor 4 (CXCR4) play a critical role in progenitor cell homing, mobilization and differentiation.
Marjan Jahangiri   +31 more
core   +2 more sources

Effects of Dietary Fiber Type on Growth Performance, Serum Parameters and Fecal Microbiota Composition in Weaned and Growing-Finishing Pigs

open access: yesAnimals, 2022
The objective of this study was to evaluate the effects of different SDF to IDF ratios on growth performance, serum indexes and fecal microbial community in pigs.
Zhiqian Lv   +5 more
doaj   +1 more source

SDF-1α-induced platelet aggregation via CXCR4 and PI3 kinase.

open access: yes, 2017
(A) Data on platelet aggregation analyzed using platelet-rich plasma. Platelets were stimulated with 100 ng/ml, 250 ng/ml, and 1 μg/ml SDF-1α. (B) 1 μg/ml SDF-1α–induced platelet aggregation with or without pretreatment with 5 μg/ml AMD3100 for 10 min ...
Kohji Kasahara (3628436)   +10 more
core   +1 more source

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