Results 21 to 30 of about 29,746,039 (283)
Author Correction: Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration. [PDF]
Chen D +8 more
europepmc +3 more sources
SDF-1 in myocardial repair [PDF]
Stem cell therapy for the prevention and treatment of cardiac dysfunction holds significant promise for patients with ischemic heart disease. Excitingly early clinical studies have demonstrated safety and some clinical feasibility, while at the same time studies in the laboratory have investigated mechanisms of action and strategies to optimize the ...
M S, Penn +3 more
openaire +2 more sources
SDF-1 promotes endochondral bone repair during fracture healing at the traumatic brain injury condition. [PDF]
The objective of this study was to investigate the role of stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, on bone healing and whether SDF-1 contributes to accelerating bone repair in traumatic brain injury (TBI)/fracture model.Real-time ...
Xiaoqi Liu +6 more
doaj +1 more source
Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration [PDF]
AbstractStromal cell-derived factor 1 (SDF-1) is a chemokine that can be expressed in injured cardiomyocytes after myocardial infarction (MI). By combining with its receptor CXCR4, SDF-1 induced stem and progenitor cells migration. CXCR7, a novel receptor for SDF-1, has been identified recently.
Dong Chen +8 more
openaire +2 more sources
Upregulation of stromal cell-derived factor 1 (SDF-1) is associated with macrophage infiltration in renal ischemia-reperfusion injury. [PDF]
Stromal cell-derived factor-1(SDF-1) is a chemotactic and angiogenic factor that mediates the repair of various tissues. As macrophages are important contributors to ischemic kidney injury, we examine the role of SDF-1 in a rodent model of ischemia ...
Xin Wan +6 more
doaj +1 more source
A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor
CXC chemokine receptor 4 (CXCR4) is a co-receptor for HIV-1 entry into target cells. Its natural ligand, the chemokine SDF-1, inhibits viral entry mediated by this receptor. However, the broad expression pattern of CXCR4 and its critical roles in various
Suiyi Tan +13 more
doaj +1 more source
Stromal cell-derived factor 1 (SDF-1, also known as CXCL12) and its receptor CXCR4 have shown to play a role in the homing and engraftment of hematopoietic stem and progenitor cells.
Yi Li +5 more
doaj +1 more source
Our previous studies showed that in a mouse model in which PI3K-AKT activation was increased (YF mice), osteoclast numbers and levels of SDF-1, a chemokine, were augmented.
Naga Suresh Adapala +4 more
doaj +1 more source
CXCL12 (SDF-1)/CXCR4 Pathway in Cancer [PDF]
Abstract Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane receptors, are major regulators of cell trafficking and adhesion. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; CD184).
Beverly A, Teicher, Simon P, Fricker
openaire +2 more sources
Histological Examination of Engineered Mesenchymal Stem Cells Improve Bladder Function in Rat
This study was undertaken to examine the effects and to investigate the relevant mechanisms of overexpressing stromal cell-derived factor-1 (SDF-1) produced by engineered mesenchymal stem cells, in a neurogenic bladder (NB) rat model. Sprague-Dawley (SD)
Eun Kyung Cho, Seung Hwan Jeon
doaj +1 more source

