Stem cells migration during skeletal muscle regeneration - the role of Sdf-1/Cxcr4 and Sdf-1/Cxcr7 axis [PDF]
Cell Adhesion & Migration, 2016 The skeletal muscle regeneration occurs due to the presence of tissue specific stem cells - satellite cells. These cells, localized between sarcolemma and basal lamina, are bound to muscle fibers and remain quiescent until their activation upon muscle ...
Kamil Kowalski +12 more
semanticscholar +7 more sources
Association of SDF-1 and its receptor CXCR4 polymorphisms on the susceptibility of diabetic retinopathy in the Taiwanese population [PDF]
Frontiers in Genetics, 2023 Stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine 4 (CXCR4) have been demonstrated to play critical roles in diabetic retinopathy (DR).
Shu-Yen Peng +17 more
doaj +2 more sources
Prognostic significance of plasma SDF-1 in acute ischemic stroke patients with diabetes mellitus: the CATIS trial [PDF]
Cardiovascular Diabetology, 2023 Background and objectives Evidence on the associations between baseline stromal cell-derived factor (SDF)-1 and clinical outcomes in acute ischemic stroke patients is lacking.
Shoujiang You +11 more
doaj +2 more sources
Impact of SDF-1 and AMD3100 on Hair Follicle Dynamics in a Chronic Stress Model [PDF]
BiomoleculesChronic stress is a common cause of hair loss, involving inflammatory responses and changes in cellular signaling pathways. This study explores the mechanism of action of the SDF-1/CXCR4 signaling axis in chronic stress-induced hair loss.
Yinglin Zhao +4 more
doaj +2 more sources
Protection of stromal cell-derived factor-1 SDF-1/CXCL12 against proteases yields improved skin wound healing [PDF]
Frontiers in ImmunologySDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical applications in
Rafaela Vaz Sousa Pereira +12 more
doaj +2 more sources
KLF9 inhibits the proliferation, invasion, and migration of renal cell carcinoma through the SDF‐1/CXCR4 axis [PDF]
Kaohsiung Journal of Medical Sciences, 2023 Altered Krüppel‐like factor 9 (KLF9) expression can regulate the progression of several cancers, including renal cell carcinoma (RCC). This study was conducted to investigate the role of KLF9 in the proliferation, invasion, and migration of RCC cells via
Peng Yu +6 more
doaj +2 more sources
SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway [PDF]
Arthritis Research & TherapyObjective Osteoarthritis (OA) is the most common form of joint disease. Currently, OA treatment is limited to controlling symptoms. Our previous study showed that stromal cell-derived factor 1 (SDF-1) delayed the progression of OA to a certain extent ...
Yanping Zhao +8 more
doaj +2 more sources
Stem Cell Research & Therapy, 2019 Endometrial regenerative cells (ERCs) are a new type of mesenchymal-like stromal cells, and their therapeutic potential has been tested in a variety of disease models. SDF-1/CXCR4 axis plays a chemotaxis role in stem/stromal cell migration.
Xiang Li +12 more
doaj +2 more sources
SDF-1/CXCR4 Signaling Maintains Stemness Signature in Mouse Neural Stem/Progenitor Cells
Stem Cells International, 2017 SDF-1 and its primary receptor, CXCR4, are highly expressed in the embryonic central nervous system (CNS) and play a crucial role in brain architecture. Loss of SDF-1/CXCR4 signaling causes abnormal development of neural stem/progenitor cells (NSCs/NPCs)
Shih-Yin Ho +9 more
doaj +2 more sources
The effects of SDF-1 combined application with VEGF on femoral distraction osteogenesis in rats [PDF]
Open Life SciencesBone regeneration and mineralization can be achieved by means of distraction osteogenesis (DO). In the present study, we investigated the effect of stromal cell-derived factor 1 (SDF-1) and vascular endothelial growth factor (VEGF) on the new bone ...
Fu Fangang +8 more
doaj +2 more sources