Results 1 to 10 of about 46,821 (157)

CXCL12/SDF-1 and CXCR4 [PDF]

Frontiers in Immunology, 2015
Chemokines are a large family of structurally related chemoattractive cytokines, which have four conserved cysteines forming two disulfide bonds, and act through seven-transmembrane-spanning receptors coupled to heterotrimeric GTP-binding proteins (G-protein-coupled receptors).
Takashi eNagasawa
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Association of SDF-1 and its receptor CXCR4 polymorphisms on the susceptibility of diabetic retinopathy in the Taiwanese population [PDF]

Frontiers in Genetics, 2023
Stromal cell-derived factor-1 (SDF-1) and its receptor CXC chemokine 4 (CXCR4) have been demonstrated to play critical roles in diabetic retinopathy (DR).
Shu-Yen Peng, Shu-Yen Peng, Chih-Chun Chuang, Chih-Chun Chuang, Chih-Chun Chuang, Yih-Shiou Hwang, Yih-Shiou Hwang, Yih-Shiou Hwang, Yih-Shiou Hwang, Chieh-Hung Yen, Chieh-Hung Yen, Chieh-Hung Yen, Chieh-Hung Yen, Chia-Yi Lee, Chia-Yi Lee, Chia-Yi Lee, Shun-Fa Yang, Shun-Fa Yang   +17 more
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Impact of SDF-1 and AMD3100 on Hair Follicle Dynamics in a Chronic Stress Model [PDF]

Biomolecules
Chronic stress is a common cause of hair loss, involving inflammatory responses and changes in cellular signaling pathways. This study explores the mechanism of action of the SDF-1/CXCR4 signaling axis in chronic stress-induced hair loss.
Yinglin Zhao, Wenzi Liang, Zhehui Liu, Xiuwen Chen, Changmin Lin   +4 more
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Prognostic significance of plasma SDF-1 in acute ischemic stroke patients with diabetes mellitus: the CATIS trial [PDF]

Cardiovascular Diabetology, 2023
Background and objectives Evidence on the associations between baseline stromal cell-derived factor (SDF)-1 and clinical outcomes in acute ischemic stroke patients is lacking.
Shoujiang You, Hongyu Chen, Mengyuan Miao, Jigang Du, Bizhong Che, Tan Xu, Chun-Feng Liu, Yonghong Zhang, Jiang He, Xiaoyan Zhong, Yongjun Cao, Chongke Zhong   +11 more
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SDF-1/CXCL12 and CXCR4 gene variants, and elevated serum SDF-1 levels are associated with preeclampsia

Hypertension in Pregnancy, 2017
Objective: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3′A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE).
Savas Karakus, Binnur Bagci, Gokhan Bagci, Enver Sancakdar, Caglar Yildiz, Ozlem Akkar, Ali Cetin   +6 more
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SDF-1 loaded dECM patch improves cardiac function in rats after myocardial ischemia [PDF]

Stem Cell Research & Therapy
Background Ischemic heart disease (IHD) remains a global health challenge, characterized by irreversible cardiomyocyte loss and pathological ventricular remodeling.
Jing Zhang, Wanqing Lin, Qian Li, Shiyu Cui, Xiang Bu, Xin Jiang, Aiqun Ma, Tingzhong Wang   +7 more
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Protection of stromal cell-derived factor-1 SDF-1/CXCL12 against proteases yields improved skin wound healing [PDF]

Frontiers in Immunology
SDF-1/CXCL12 is a unique chemotactic factor with multiple functions on various types of precursor cells, all carrying the cognate receptor CXCR4. Whereas individual biological functions of SDF-1/CXCL12 have been well documented, practical applications in
Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker   +12 more
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KLF9 inhibits the proliferation, invasion, and migration of renal cell carcinoma through the SDF‐1/CXCR4 axis [PDF]

Kaohsiung Journal of Medical Sciences, 2023
Altered Krüppel‐like factor 9 (KLF9) expression can regulate the progression of several cancers, including renal cell carcinoma (RCC). This study was conducted to investigate the role of KLF9 in the proliferation, invasion, and migration of RCC cells via
Peng Yu, Long Cheng, Wei‐Mu Xia, Ding‐Yi Liu, Jia‐Shun Yu, Yan‐Feng Zhou, Yong‐Jun Zheng   +6 more
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SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway [PDF]

Arthritis Research & Therapy
Objective Osteoarthritis (OA) is the most common form of joint disease. Currently, OA treatment is limited to controlling symptoms. Our previous study showed that stromal cell-derived factor 1 (SDF-1) delayed the progression of OA to a certain extent ...
Yanping Zhao, Dan Lin, Xiaoying Zhu, Jingyao Yan, Yan Liang, Yanli Wang, Tianqi Dai, Zhiyi Zhang, Shuya Wang   +8 more
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The effects of SDF-1 combined application with VEGF on femoral distraction osteogenesis in rats [PDF]

Open Life Sciences
Bone regeneration and mineralization can be achieved by means of distraction osteogenesis (DO). In the present study, we investigated the effect of stromal cell-derived factor 1 (SDF-1) and vascular endothelial growth factor (VEGF) on the new bone ...
Fu Fangang, Li Mengqi, Yang Shuye, Du Gangqiang, Xu Yingjiang, Jiang Jianhao, Jia Long, Zhang Kai, Li Peng   +8 more
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