Development And Application Of Fluorescent SDF-1 Derivatives [PDF]
Future Medicinal Chemistry, 2012 SDF-1/CXCR4 signaling plays key roles in directed cell migration under physiological and pathological conditions. To develop agonist-based CXCR4 probes for detection of CXCR4 expression on cell lines and metastatic tumors, SAR analyses of fluorescent SDF-1 derivatives were carried out.Several SDF-1 derivatives with a single fluorescent label were ...
Masuda, Ryo +8 more
openaire +5 more sources
Spatiotemporal presentation of exogenous SDF-1 with PLGA nanoparticles modulates SDF-1/CXCR4 signaling axis in the rodent cortex [PDF]
Biomaterials Science, 2017 Temporal control over SDF-1 release via PLGA nanoparticles differentially affects the SDF-1/CXCR4 signaling axis across the adult cortex.
D. Dutta +5 more
openaire +3 more sources
Factores inmunogenéticos relacionados con la resistencia/susceptibilidad a la infección por el VIH-1 y su progresión hacia SIDA [PDF]
, 2006 [spa] Los individuos expuestos al VIH-1 y no infectados y los pacientes infectados no progresores de larga duración son situaciones modelo para estudiar factores del huésped implicados en conferir resistencia a la infección / progresión y su conocimiento
Soriano Viladomiu, Alex
core +6 more sources
SDF-1 Attenuates Oocyte Quality Decline During Reproductive Aging Through Autophagy-Enhanced Stress Granule Scavenging. [PDF]
Adv Sci (Weinh)SDF‐1 levels decline significantly with maternal aging. Exogenous supplementation restores meiotic spindle morphology, chromosomal alignment, and mitochondrial function while reducing oxidative stress in aged oocytes. Mechanistically, SDF‐1 enhances autophagic activity to clear accumulated stress granules, thereby rescuing fertilization competence and ...
Long R +12 more
europepmc +2 more sources
Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults [PDF]
Endocrinology and Metabolism, 2023 Background Despite the protective effects of stromal cell-derived factor 1 (SDF-1) in stimulating muscle regeneration shown in experimental research, there is a lack of clinical studies linking circulating SDF-1 concentrations with muscle phenotypes.
Sunghwan Ji +9 more
doaj +1 more source
CXCL12/SDF-1 in IgG4-Related Disease [PDF]
Frontiers in Pharmacology, 2021 Background: SDF-1/CXCL12 is a chemokine with pleiotropic functions in hematopoietic stem cell niche homeostasis, germinal center architecture, B cell maturation, neoangiogenesis, and fibrosis. Recently, the CXCL12/CXCR4/CXCR7 axis was associated with cancer metastasis and autoimmune diseases.
Capecchi R. +9 more
openaire +3 more sources
Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. [PDF]
PLoS ONE, 2012 Stromal cell-derived factor 1 (SDF-1/CXCL12/PBSF) plays important roles in the biological and physiological functions of haematopoietic and mesenchymal stem cells.
Koichi Murata +12 more
doaj +1 more source
Radiographic Changes to Silver Diamine Fluoride Treated Carious Lesions after a Rinsing Step
Dentistry Journal, 2022 Silver diamine fluoride (SDF) is radiopaque. This in vitro study compares the changes in the radiopacity of carious lesions after SDF application, potassium iodide (PI) application, and water rinse.
Zaher Jabbour +3 more
doaj +1 more source
Transcriptome analysis reveals the mechanism of stromal cell-derived factor-1 and exendin-4 synergistically promoted periodontal ligament stem cells osteogenic differentiation [PDF]
PeerJ, 2021 Stromal cell-derived factor-1 (SDF-1) and Exendin-4 (EX-4) play beneficial roles in promoting periodontal ligament stem cells (PDLSCs) osteogenic differentiation, while the detailed mechanism has not been clarified.
Wenyan Kang +5 more
doaj +2 more sources
Materials & Design, 2021 Background: SDF-1/CXCR4 axis plays a critical role in the mobilization and regeneration of host-derived cells. Little is known around the role of SDF-1 gene on bone regeneration.
Zhaoqi Sun +3 more
doaj +1 more source