Results 11 to 20 of about 27,322,199 (337)
Hypertension in Pregnancy, 2017 Objective: We aimed to compare the frequencies of stromal cell-derived factor-1 (SDF-1) 3′A and CXCR4 single-nucleotide polymorphisms (SNPs) and serum SDF-1 levels in patients with preeclampsia (PE).
Savas Karakus +6 more
doaj +5 more sources
Bone Reports, 2019 Our previous studies showed that in a mouse model in which PI3K-AKT activation was increased (YF mice), osteoclast numbers and levels of SDF-1, a chemokine, were augmented.
Naga Suresh Adapala +4 more
doaj +3 more sources
CXCL12 (SDF-1)/CXCR4 Pathway in Cancer [PDF]
Clinical Cancer Research, 2010 Abstract Chemokines, small proinflammatory chemoattractant cytokines that bind to specific G-protein-coupled seven-span transmembrane receptors, are major regulators of cell trafficking and adhesion. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; CD184).
B. Teicher, S. Fricker
semanticscholar +3 more sources
Frontiers in Immunology, 2015 Chemokines are a large family of structurally related chemoattractive cytokines, which have four conserved cysteines forming two disulfide bonds, and act through seven-transmembrane-spanning receptors coupled to heterotrimeric GTP-binding proteins (G-protein-coupled receptors).
Takashi eNagasawa
doaj +3 more sources
Higher Plasma Stromal Cell-Derived Factor 1 Is Associated with Lower Risk for Sarcopenia in Older Asian Adults [PDF]
Endocrinology and Metabolism, 2023 Background Despite the protective effects of stromal cell-derived factor 1 (SDF-1) in stimulating muscle regeneration shown in experimental research, there is a lack of clinical studies linking circulating SDF-1 concentrations with muscle phenotypes.
Sunghwan Ji +9 more
doaj +1 more source
CXCL12/SDF-1 in IgG4-Related Disease [PDF]
Frontiers in Pharmacology, 2021 Background: SDF-1/CXCL12 is a chemokine with pleiotropic functions in hematopoietic stem cell niche homeostasis, germinal center architecture, B cell maturation, neoangiogenesis, and fibrosis. Recently, the CXCL12/CXCR4/CXCR7 axis was associated with cancer metastasis and autoimmune diseases.
Capecchi R. +9 more
openaire +3 more sources
Transcriptome analysis reveals the mechanism of stromal cell-derived factor-1 and exendin-4 synergistically promoted periodontal ligament stem cells osteogenic differentiation [PDF]
PeerJ, 2021 Stromal cell-derived factor-1 (SDF-1) and Exendin-4 (EX-4) play beneficial roles in promoting periodontal ligament stem cells (PDLSCs) osteogenic differentiation, while the detailed mechanism has not been clarified.
Wenyan Kang +5 more
doaj +2 more sources
Stromal cell-derived factor 1 regulates the actin organization of chondrocytes and chondrocyte hypertrophy. [PDF]
PLoS ONE, 2012 Stromal cell-derived factor 1 (SDF-1/CXCL12/PBSF) plays important roles in the biological and physiological functions of haematopoietic and mesenchymal stem cells.
Koichi Murata +12 more
doaj +1 more source
Crosstalk between SDF-1/CXCR4 and SDF-1/CXCR7 in cardiac stem cell migration [PDF]
Scientific Reports, 2015 AbstractStromal cell-derived factor 1 (SDF-1) is a chemokine that can be expressed in injured cardiomyocytes after myocardial infarction (MI). By combining with its receptor CXCR4, SDF-1 induced stem and progenitor cells migration. CXCR7, a novel receptor for SDF-1, has been identified recently.
Dong Chen +8 more
openaire +3 more sources
Journal of Bone and Mineral Metabolism, 2020 Recent studies have indicated the potential of stem cell therapy in combination with cytokines to restore the bone repair via migration and homing of stem cells to the defected area. The present study aimed to investigate the mobilization and recruitment of mesenchymal stem cells (MSCs) in response to SDF-1.Herein, the knockout rat model of the bone ...
Heli Zhang +5 more
semanticscholar +3 more sources