Results 1 to 10 of about 77,141 (297)

Application of a novel nanoemulsion adjuvant for rabies vaccine which stabilizes a Krebs cycle intermediate (SDH) in an animal model [PDF]

Human Vaccines & Immunotherapeutics, 2019
Rabies is the most lethal zoonotic, vaccine-preventable viral disease in the world. Its treatment is complicated by insufficient vaccine supply and the requirement for four to five repeated injections, as commercially available inactivated rabies lack ...
Liu Ze, Li Zonglin, Wu Ya’Nan, Song Shaohui, Yang Huijuan, Cai Wei, Weidong Li, Guoyang Liao   +7 more
doaj   +2 more sources

Spinal Dorsal Horn Neurons Receiving Descending Input from the Primary Somatosensory Cortex Contribute to Aβ Fiber-Induced Neuropathic Allodynia in Male Rats [PDF]

Cells
Mechanical allodynia is the predominant symptom of neuropathic pain following peripheral nerve injury (PNI) and is characterized by pain evoked by innocuous sensory signals transmitted through low-threshold mechanoreceptive primary afferents, including ...
Sho Shinotsuka, Eriko I, Daichi Sueto, Kazuki Fujimori, Ken Yamaura, Makoto Tsuda   +5 more
doaj   +2 more sources

Efficient identification of new small molecules targeting succinate dehydrogenase in non-small cell lung cancer [PDF]

Cancer Cell International
Background Lung cancer treatment efficacy remains a challenge due to limited therapeutic targets. Succinate dehydrogenase (SDH) enzyme, a crucial enzyme linking the citric acid cycle and the electron transport chain, is implicated in cancer metabolism ...
Luis Silva, Nicholas Skiados, Nikitha Murugavel, Karen Cover, Nastassja Luna, Manish K. Gupta, Stephanie C. Contreras, Terrence E. O’Brien, Wen Cai Zhang,   +8 more
doaj   +2 more sources

Exome sequencing and SDH (A, B) immunohistochemistry of canine Pheochromocytomas [PDF]

Iraqi Journal of Veterinary Sciences, 2022
Pheochromocytomas (PCs) are tumors originating from the chromaffin cells of the adrenal medulla. In people, there are highly correlated to inherited gene mutations in the succinate dehydrogenase (SDH) pathway; however, to date, little work has been done ...
Firas M. Abed, Michael J. Dark
doaj   +1 more source

Investigating the rate and factors of approach to desalinated water in Kashan and Aran-Bidgol cities [PDF]

International Archives of Health Sciences, 2023
Objectives: In recent years, due to the inappropriate quality of distributed water by the public water network in many parts of Iran, especially in the central areas, the use of desalinated water has been widely developed. Therefore, for any planning and
Davarkhah Rabbani, Rouhullah Dehghani, Mohammad Bagher Miranzadeh, Gholamreza Reza Mostafaii, Fatemeh Akbarzadeh   +4 more
doaj   +1 more source

Succinate dehydrogenase-deficient renal cell carcinoma: A retrospective study, 1999–2018

South African Journal of Oncology, 2023
Background: Succinate dehydrogenase-deficient (SDH-deficient) renal cell carcinoma (RCC) is a rare subtype of RCC. Approximately 0.05% – 0.2% of RCCs are SDH-deficient. It is usually associated with a pathogenic germline variant of the enzyme.
Ella Morrison, Jacqueline Goedhals, Shireen Pretorius, Gina Joubert, Anthony J. Gill, Gerhard van der Westhuizen   +5 more
doaj   +1 more source

Acrylamide induced histochemical and immunohistochemical alterations in rat kidney cortex [PDF]

Journal of Bioscience and Applied Research, 2015
Acrylamide represents an industrial chemical and has become one of the main public health concerns since it was detected in extensively consumed food items.
Safia Mohamed Hassan, Eman Ahmed Youssef
doaj   +1 more source

Rethinking the Theory of Change for Health in All Policies; Comment on “Health Promotion at Local Level in Norway: The Use of Public Health Coordinators and Health Overviews to Promote Fair Distribution Among Social Groups” [PDF]

International Journal of Health Policy and Management, 2018
This commentary discusses the interesting and surprising findings by Hagen and colleagues, focusing on the role of the public health coordinator as a Health in All Policies (HiAP) tool.
Ditte Heering Holt
doaj   +1 more source

The impact of social determinants of health on textbook oncological outcomes and overall survival in locally advanced non–small cell lung cancerCentral MessagePerspective

JTCVS Open, 2023
Objectives: Textbook oncological outcome (TOO) is a composite metric for surgical outcomes, including non–small cell lung cancer (NSCLC). We hypothesized that social determinants of health (SDH) can affect both the attainment of TOO and the overall ...
Ahmed Alnajar, MD, MSPH, Syed S. Razi, MD, Karishma Kodia, MD, Nestor Villamizar, MD, Dao M. Nguyen, MD, MSc, FRCSC, FACS   +4 more
doaj   +1 more source

Back to the Individual-Social Life in patient with Avascular necrosis of femur by Bioresonance Technology (Case Report)

Social Determinants of Health, 2018
Background: More than 20,000 people annually develop avascular necrosis (AVN) worldwide, most of whom aged 20 to 50 years, and should refer to orthopedic surgeons for treatment.
ahmad shafaeizadeh
doaj   +1 more source