Proteogenomic characterization of cholangiocarcinoma
Proteogenomic characterization of cholangiocarcinoma with therapeutic strategies Abstract Background and Aims Cholangiocarcinoma (CCA) is a highly heterogeneous cancer with limited understanding and few effective therapeutic approaches. We aimed at providing a proteogenomic CCA characterization to inform biological processes and treatment ...
Mengjie Deng +18 more
wiley +1 more source
The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro +14 more
wiley +1 more source
Molecular features and genetic markers of gastrointestinal stromal tumors
Gastrointestinal stromal tumors (GISTs) are the most spread mesenchymal tumors located within the gastrointestinal tract that have particular clinico-morphological, immunohistochemical and molecular characteristics.
N. N. Mazurenko, I. МЮ Tsyganova
doaj +1 more source
Impact of topology on layer 2 switched QoS sensitive services [PDF]
High-bandwidth QoS sensitive services such as large scale video surveillance generally depend on provisioned capacity delivered by circuit-switched technology such as SONET/SDH.
Colle, Didier +7 more
core +2 more sources
Epidemiology of subdural haemorrhage during infancy: A population-based register study. [PDF]
OBJECTIVES:To analyse subdural haemorrhage (SDH) during infancy in Sweden by incidence, SDH category, diagnostic distribution, age, co-morbidity, mortality, and maternal and perinatal risk factors; and its association with accidents and diagnosis of ...
Ulf Högberg +6 more
doaj +1 more source
Capturing the social determinants of health at the individual level: a pilot study
Objective and importance of study: Considerable evidence suggests that adverse social determinants of health (SDH), such as poor education, unemployment, food and housing insecurity, interpersonal violence, inadequate social support and poverty, are key ...
Kate E Neadley +7 more
doaj +1 more source
Safe Implementation of Mechanical Thrombectomy in Acute Stroke Patients with Major Arterial Occlusion and Concomitant Subdural Hematoma [PDF]
Mechanical thrombectomy (MT) alone in cases of large-vessel acute ischemic stroke (AIS) with a concomitant subdural hematoma (SDH) seems feasible and safe, but there's still a lack of evidence in the clinical literature. We report three cases of AIS with
Yong-Won Kim +4 more
doaj +1 more source
Surface Shubnikov-de Hass oscillations and non-zero Berry phases of the topological hole conduction in Tl$_{1-x}$Bi$_{1+x}$Se$_2$ [PDF]
We report the observation of two-dimensional Shubnikov-de Hass (SdH) oscillations in the topological insulator Tl$_{1-x}$Bi$_{1+x}$Se$_2$. Hall effect measurements exhibited electron-hole inversion in samples with bulk insulating properties.
Eguchi, G. +4 more
core +2 more sources
Subtitling for the Deaf and the Hard-of-Hearing in Poland: History, Problems, Challenges
The article presents the history of development of subtitles for the Deaf and hard of hearing in Poland from 2009 to 2019. It also describes the present state of art concerning this type of audiovisual translation.
Monika Szczygielska
doaj +1 more source
Rapid Spontaneous Resolution of Contralateral Acute Subdural Hemorrhage Caused by Overdrainage of Chronic Subdural Hemorrhage [PDF]
Background Since the first report of a rapidly resolved subdural hemorrhage (SDH) in 1986, few additional case reports have been presented in the literature. Case Report An 82-year-old female patient presented with a SDH over the left convexity.
Minwook Yoo, Jung-Soo Kim
doaj +1 more source

