Results 81 to 90 of about 25,164,155 (279)

Parameter Estimation for Thurstone Choice Models

, 2017
We consider the estimation accuracy of individual strength parameters of a Thurstone choice model when each input observation consists of a choice of one item from a set of two or more items (so called top-1 lists). This model accommodates the well-known
Vojnovic, Milan, Yun, Se-Young
core   +1 more source

Recurrent Genomic Alterations in BCRi‐Experienced CLL Patients Treated With Venetoclax: Extended Phase 2 Follow‐Up

American Journal of Hematology, EarlyView.
Jennifer A. Woyach, Relja Popovic, Emily L. Rossi, Sanjana Singh, Toshihiko Oki, Tanya S. Rosenberg, Chen Qian, Michael Moran, Zihuan Liu, Michelle Boyer, Jeffrey Jones, Richard R. Furman, William Wierda, Jason Gotlib, Stephen J. Schuster, Brenda Chyla, Matthew S. Davids   +16 more
wiley   +1 more source

Early clinical pharmacology evaluation of the novel anti‐inflammatory macrolide, glasmacinal (EP395): tolerability, pharmacokinetics and drug interactions

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh, Kate Hanrott, Olof Breuer, Johan Bylund, Björn Schultze, Virginia Norris   +5 more
wiley   +1 more source

Antecedents of Patient Loyalty: Exploring Mediating and Moderating Paradigms in Public Hospitals

Patient Preference and Adherence
Abid Hussain,1 Shahida Kanwel,2 Sania Khan,3 Wadi B Alonazi,4 Azam Malik,3 Ali Ahmed Khan5 1School of Nursing, Shandong Xiehe University, Jinan, 250109, People’s Republic of China; 2School of Management, Jiangsu University, Zhenjiang, Jiangsu, 212013 ...
Hussain A, Kanwel S, Khan S, Alonazi WB, Malik A, Khan AA   +5 more
doaj  

A comparative examination of policy and models of disability in Korea and the UK [PDF]

, 2012
Over the last three decades, the understanding of disability has changed substantially, changes in theoretical debates and policy on disability now encourage society to understand and treat disabled people as ordinary citizens.
Brandon, Toby, Hwang, Se Kwang
core  

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Content of micro- and macroelements in patients with autoimmune thyroiditis and subclinical hypothyroidism

Patologìâ
Aim. To investigate the content of iodine (I), selenium (Se), zinc (Zn), magnesium (Mg), calcium (Ca) and vitamin D, the thyroid volume and thyroid functional state in patients with autoimmune thyroiditis (AIT) and subclinical hypothyroidism (SCH), to ...
V. I. Kravchenko, T. F. Zakharchenko, O. V. Rakov, K. Yu. Ivaskiva, O. I. Kovzun   +4 more
doaj   +1 more source

A phase 1 evaluation of inhaled oxytocin: Physiologically‐based pharmacokinetic model informed dosing of a novel heat‐stable oxytocin delivery system

British Journal of Clinical Pharmacology, EarlyView.
Aim To develop and validate a physiologically‐based pharmacokinetic (PBPK) model enabling inhaled oxytocin dose selection for clinical evaluation. Subsequently, to conduct a phase 1 study investigating the pharmacokinetics and safety of selected doses of an optimized inhaled oxytocin product in healthy, non‐pregnant female participants.
Pete Lambert, Carl M. J. Kirkpatrick, Rory Marriott, Siladitya Ray Chaudhuri, David Polidori, Bart Remmerie, Michelle P. McIntosh   +6 more
wiley   +1 more source

Application of damage mechanics in percussive drilling modelling [PDF]

, 2005
A stationary-periodic quasi-static model of rock percussive deep drilling is introduced. First, an auxiliary problem of stationary indentation of a rigid indentor is considered.
Mikhailov, SE, Namestnikova, IV
core  

Chiral edge mode in the coupled dynamics of magnetic solitons in a honeycomb lattice

, 2017
Motivated by a recent experimental demonstration of a chiral edge mode in an array of spinning gyroscopes, we theoretically study the coupled gyration modes of topological magnetic solitons, vortices and magnetic bubbles, arranged as a honeycomb lattice.
Kim, Se Kwon, Tserkovnyak, Yaroslav
core   +1 more source