Results 51 to 60 of about 3,539,778 (300)

Arctic sea ice simulation in the PlioMIP ensemble [PDF]

Climate of the Past, 2016
Eight general circulation models have simulated the mid-Pliocene warm period (mid-Pliocene, 3.264 to 3.025 Ma) as part of the Pliocene Modelling Intercomparison Project (PlioMIP).
F. W. Howell, A. M. Haywood, B. L. Otto-Bliesner, F. Bragg, W.-L. Chan, M. A. Chandler, C. Contoux, Y. Kamae, A. Abe-Ouchi, N. A. Rosenbloom, C. Stepanek, Z. Zhang   +11 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Factors influencing the stable carbon isotopic composition of suspended and sinking organic matter in the coastal Antarctic sea ice environment [PDF]

, 2011
A high resolution time-series analysis of stable carbon isotopic signatures in particulate organic carbon (δ13CPOC) and associated biogeochemical parameters in sea ice and surface waters provides an insight into the factors affecting δ13CPOC in the ...
Carson, D. S., Ganeshram, R.S., R. S. Ganeshram, S. F. Henley, A. E. Fallick, Fallick, A.E., J. Dougans, A. Clarke, Ganeshram, R. S.; id_orcid, Annett, A.L., Annett, Amber, Weston, K., Henley, S.F., Annett, A. L., Ganeshram, R. S., Carson, D.S., D. S. Carson, K. Weston, Dougans, J., Fallick, A. E., A. L. Annett, Crosta, X., A. Tait, X. Crosta, Henley, S. F., Tait, A., Clarke, A.   +26 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Using Sea-Level Data to Constrain the Contribution of the Greenland Ice Sheet to Contemporary and Recent Sea-Level Change [PDF]

, 2010
Due to the potentially wide-reaching impacts on climate and sea-level change of a declining Greenland Ice Sheet (GrIS), the mass balance of the past decade has caused concern that the ice sheet is reacting to increased temperatures of the industrial era ...
Wake, Leanne Mary, WAKE, LEANNE,MARY
core  

Pliocene Ice Sheet Modelling Intercomparison Project (PLISMIP) – experimental design [PDF]

Geoscientific Model Development, 2012
During the mid-Pliocene warm period (3.264 to 3.025 million years ago), global mean temperature was similar to that predicted for the next century and atmospheric carbon dioxide concentrations were slightly higher than today.
A. M. Dolan, S. J. Koenig, D. J. Hill, A. M. Haywood, R. M. DeConto   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Simulated global-mean sea level changes over the last half-millennium [PDF]

, 2006
Simulations of the last 500 yr carried out using the Third Hadley Centre Coupled Ocean-Atmosphere GCM (HadCM3) with anthropogenic and natural (solar and volcanic) forcings have been analyzed.
Tett, S. F. B., Gregory, J. M., Lowe, J. A.   +2 more
core   +1 more source

Simulating sea-ice deformation in viscous-plastic sea-ice models with CD-grids

CoRR, 2023
Linear Kinematic Features (LKFs) are found everywhere in the Arctic sea-ice cover. They are strongly localized deformations often associated with the formation of leads and pressure ridges. Viscous-plastic sea-ice models start to produce LKFs at high spatial grid resolution, typically with a grid spacing below 5 km.
Carolin Mehlmann, GiacGiacomo Capodaglio, Sergey Danilov   +2 more
openaire   +2 more sources