Results 101 to 110 of about 2,565,243 (371)

Quantifying the influence of sea ice on ocean microseism using observations from the Bering Sea, Alaska [PDF]

open access: yes, 2011
Microseism is potentially affected by all processes that alter ocean wave heights. Because strong sea ice prevents large ocean waves from forming, sea ice can therefore significantly affect microseism amplitudes.
McNamara, Daniel E., Tsai, Victor C.
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

A direct helicopter EM sea ice thickness inversion, assessed with synthetic and field data [PDF]

open access: yes, 2007
Accuracy and precision of helicopter electromagneticHEM sounding are the essential parameters for HEM seaicethickness profiling. For sea-ice thickness research, thequality of HEM ice thickness estimates must be better than10 cm to detect potential ...
Haas, Christian   +2 more
core  

Arctic and Antarctic Sea Ice Change: Contrasts, Commonalities, and Causes.

open access: yesAnnual Review of Marine Science, 2019
Arctic sea ice has declined precipitously in both extent and thickness over the past four decades; by contrast, Antarctic sea ice has shown little overall change, but this masks large regional variability.
T. Maksym
semanticscholar   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Taking stock of arctic sea ice and climate [PDF]

open access: yes, 2009
The relationship among the cause-and-effect of the Arctic atmosphere, sea ice, and ocean is discussed. The increased vulnerability of the Arctic system to anomalous atmospheric forcing can be argued from the perspective that recent ice loss is the result
Francis, Jennifer   +3 more
core   +2 more sources

Version 2 of the EUMETSAT OSI SAF and ESA CCI sea-ice concentration climate data records

open access: yesThe Cryosphere, 2018
. We introduce the OSI-450, the SICCI-25km and the SICCI-50km climate data records of gridded global sea-ice concentration. These three records are derived from passive microwave satellite data and offer three distinct advantages compared to existing ...
T. Lavergne   +16 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Biomarker Distributions in (Sub)‐Arctic Surface Sediments and Their Potential for Sea Ice Reconstructions

open access: yesGeochemistry, Geophysics, Geosystems, 2020
To evaluate the present sea ice changes in a longer‐term perspective, the knowledge of sea ice variability on preindustrial and geological time scales is essential.
Henriette M. Kolling   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy