Results 101 to 110 of about 2,485,692 (404)
The detection, monitoring, and forecasting of sea-ice conditions, including their extremes, is very important for ship navigation and offshore activities, and for monitoring of sea-ice processes and trends.
Marko Mäkynen+24 more
doaj +1 more source
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou+13 more
wiley +1 more source
Formation and propagation of great salinity anomalies [PDF]
North Atlantic/Arctic ocean and sea ice variability for the period 1948–2001 is studied using a global Ocean General Circulation Model coupled to a dynamic/thermodynamic sea ice model forced by daily NCEP/NCAR reanalysis data [Kalnay et al., 1996 ...
Aagaard+18 more
core +1 more source
A computational fluid dynamics model for the small-scale dynamics of wave, ice floe and interstitial grease ice interaction [PDF]
The marginal ice zone is a highly dynamical region where sea ice and ocean waves interact. Large-scale sea ice models only compute domain-averaged responses. As the majority of the marginal ice zone consists of mobile ice floes surrounded by grease ice, finer-scale modelling is needed to resolve variations of its mechanical properties, wave-induced ...
arxiv
Rapid switch‐like sea ice growth and land ice–sea ice hysteresis [PDF]
Rapid and extensive growth of sea ice cover was suggested to play a major role in the sea ice switch mechanism for the glacial cycles as well as on shorter millennial scales [Gildor and Tziperman, 2000]. This mechanism also predicts a hysteresis between sea ice and land ice, such that land ice grows when sea ice cover is small and withdraws when sea ...
Eli Tziperman+5 more
openaire +3 more sources
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang+10 more
wiley +1 more source
Light Transmission Through Arctic Sea Ice - Large-Scale Studies on Seasonality and Spatial Variability [PDF]
Arctic sea ice has declined and become thinner and more seasonal during the last decade. One consequence of this is that the surface energy budget of the Arctic Ocean is changing.
Arndt, Stefanie+2 more
core
A comparison of an operational wave-ice model product and drifting wave buoy observation in the central Arctic Ocean: investigating the effect of sea ice forcing in thin ice cover [PDF]
Two drifting wave buoys were deployed in the central Arctic Ocean, north of the Laptev Sea, where there are historically no wave observations available. An experimental wave buoy was deployed alongside a commercial buoy. The inter-buoy comparison showed that the experimental buoy measured wave heights and periods accurately; so the buoy data were used ...
arxiv
Sustained ocean changes contributed to sudden Antarctic sea ice retreat in late 2016
After nearly three decades of observed increasing trends of Antarctic sea ice extent, in September-October-November 2016, there was a dramatic decrease. Here we document factors that contributed to that decrease. An atmosphere-only model with a specified
G. Meehl+7 more
semanticscholar +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock+10 more
wiley +1 more source