Results 51 to 60 of about 929,986 (341)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Importance of Ice Vertical Resolution for Snowball Climate and Deglaciation [PDF]

open access: yes, 2010
Sea ice schemes with a few vertical levels are typically used to simulate the thermodynamic evolution of sea ice in global climate models. Here it is shown that these schemes overestimate the magnitude of the diurnal surface temperature cycle by a factor
Abbot, Dorian S.   +2 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Satellite Observations for Detecting and Forecasting Sea-Ice Conditions: A Summary of Advances Made in the SPICES Project by the EU’s Horizon 2020 Programme

open access: yesRemote Sensing, 2020
The detection, monitoring, and forecasting of sea-ice conditions, including their extremes, is very important for ship navigation and offshore activities, and for monitoring of sea-ice processes and trends.
Marko Mäkynen   +24 more
doaj   +1 more source

Feasibility Study for an Ice-Based Image Monitoring System for Polar Regions Using Improved Visual Enhancement Algorithms

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
Melting and evolution of Arctic Ocean sea ice in summer are one of the main factors affecting sea ice albedo and climate. At present, remote sensing images of sea ice are mainly acquired with the help of payload platforms, such as aircraft or satellites.
Yuchen Wang   +6 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The relationship between sea ice bacterial community structure and biogeochemistry: A synthesis of current knowledge and known unknowns

open access: yesElementa: Science of the Anthropocene, 2015
Sea ice plays an important role in high latitude biogeochemical cycles, ecosystems, and climate. A complete understanding of how sea ice biogeochemistry contributes to these processes must take into account the metabolic functions of the sea ice ...
Jeff S. Bowman
doaj   +1 more source

Influence of transport and ocean ice extent on biogenic aerosol sulfur in the Arctic atmosphere [PDF]

open access: yes, 2012
The recent decline in sea ice cover in the Arctic Ocean could affect the regional radiative forcing via changes in sea ice-atmosphere exchange of dimethyl sulfide (DMS) and biogenic aerosols formed from its atmospheric oxidation, such as methanesulfonic ...
Barrie, LA   +13 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A nuclear magnetic resonance investigation of brine inclusions in Antarctic and artificial sea ice : a thesis submitted in partial fulfilment of the requirements for the degree of Master of Science in Physics at Massey University [PDF]

open access: yes, 2000
Additional images with the print copy held in the library.The aim of this thesis is to use Nuclear Magnetic Resonance (NMR) techniques to examine the brine pockets in sea ice. Both the movement of the brine pockets within the ice, and the movement of the
Furkert, Suzanne Alice
core  

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