Results 101 to 110 of about 942,530 (302)

Measuring the Impacts of Sea Level Rise on Marine Recreational Shore Fishing in North Carolina [PDF]

We develop estimates of the economic effects of sea level rise on marine recreational shore fishing in North Carolina. We estimate the relationship between angler behavior and spatial differences in beach width using the Marine Recreational Fishing ...
Ben Poulter, Christopher F. Dumas, John C. Whitehead, Okmyung Bin   +3 more
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TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Climate change adaptation and planning: An example from Kailua Beach, Oahu, Hawaii [PDF]

, 2010
The University of Hawaii Sea Grant College Program (UHSG) in partnership with the Hawaii Department of Land and Natural Resources (DLNR), Office of Conservation and Coastal Lands (OCCL) is developing a beach and dune management plan for Kailua Beach on ...
Bohlander, Andy, Eversole, Dolan
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Downstream Hydrology Reduces Glaciers' Direct Contribution to Sea‐Level Rise

Geophysical Research Letters
Glacier mass loss is a primary contributor to sea‐level rise. All prior assessments assume all glacial melt water reaches the ocean, but many mountain glaciers are located far from oceans and may be affected by the downstream systems.
David R. Rounce, Regine Hock, Alexander A. Prusevich, Danielle S. Grogan, Richard B. Lammers, Matthias Huss, Andrew Bliss, Botao Zan   +7 more
doaj   +1 more source

Improving reporting of uncertainties in sea level rise assessments [PDF]

, 2010
Sea level rise (SLR) assessments are commonly used to identify the extent that coastal populations are at risk to flooding. However, the data and assumptions used to develop these assessments contain numerous sources and types of uncertainty, which ...
Kettle, Nathan
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Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Regional spatial planning assessments for adaptation to accelerated sea level rise - an application to Martinique’s coastal zone [PDF]

Accelerated sea level rise and hurricanes are increasingly influencing human coastal activities. With respect to the projected continuation of accelerated sea level rise and global warming one must count with additional expenses for adaptation strategies
Christine Schleupner
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Climate Change and Sea Level Rise Projections for Boston [PDF]

, 2016
While the broad outlines of how climate change would impact Boston have been known for some time, it is only recently that we have developed a more definitive understanding of what lies ahead.

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