Results 111 to 120 of about 526,957 (346)

RRS James Cook Cruise 30, 26 Dec 2008-30 Jan 2009. Antarctic Deep Water Rates of Export (ANDREX) [PDF]

open access: yes, 2011
This report describes scientific activities on RRS James Cook cruise 30, “ANDREX”, westwards from 30°E and in the vicinity of latitude 60°S, between late December 2008 and late January 2009.
Bacon, S., et al,
core  

A New Global Sea Surface Salinity and Density Dataset From Multivariate Observations (1993–2016)

open access: yesFrontiers in Marine Science, 2018
Monitoring sea surface salinity and density variations is crucial to investigate the global water cycle and the ocean dynamics, and to analyse how they are impacted by climate change.
R. Droghei   +2 more
semanticscholar   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Sea-surface temperature and salinity mapping from remote microwave radiometric measurements of brightness temperature [PDF]

open access: yes
A technique to measure remotely sea surface temperature and salinity was demonstrated with a dual frequency microwave radiometer system. Accuracies in temperature of 1 C and in salinity of part thousand for salinity greater than 5 parts per thousand were
Fedors, J. C.   +2 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Mechanisms affecting the overturning response in global warming simulations [PDF]

open access: yes, 2005
Climate models used to produce global warming scenarios exhibit widely diverging responses of the thermohaline circulation (THC). To investigate the mechanisms responsible for this variability, a regional Atlantic Ocean model driven with forcing ...
Schweckendiek, Ulf, Willebrand, Jürgen
core   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Leaching Potential of Sea Water in Saline Souls

open access: yesJournal of Agricultural and Marine Sciences, 2004
Limited fresh water resources, inefficient irrigation and soil salinity reduce agricultural production in arid and semi-arid countries. This paper describes one of the uses of sea water to reduce salinity of an excessively saline soil in Oman.
A. AI Busaidi, P. Cookson
doaj   +1 more source

Remote sensing of the Chesapeake Bay plume salinity via microwave radiometry [PDF]

open access: yes
The NASA-Langley-developed L-Band microwave radiometer was used to remotely measure sea surface salinity during the Chesapeake Bay plume studies.
Kendall, B. M.
core   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

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