Results 71 to 80 of about 802,355 (333)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The last interglacial in the northern North Atlantic and adjacent areas: evidence for a more zonal climate than during the Holocene [PDF]

, 2011
We document climate conditions from the last interglacial optimum (LIO) or marine isotope stage 5e (MIS 5e) from terrestrial and oceanic sedimentary archives.
Bauch, Henning A., De Vernal, Anne, Eynaud, Frédérique, Fréchette, Bianca, Hillaire-Marcel, Claude, Van Nieuwenhove, Nicolas   +5 more
core  

Increasing occurrence of cold and warm extremes during the recent global warming slowdown. [PDF]

, 2018
The recent levelling of global mean temperatures after the late 1990s, the so-called global warming hiatus or slowdown, ignited a surge of scientific interest into natural global mean surface temperature variability, observed temperature biases, and ...
Johnson, Nathaniel C, Kosaka, Yu, Li, Xichen, Xie, Shang-Ping   +3 more
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Study on the performance of the regional air-sea coupled model on forecast accuracy of near-surface temperature and humidity in the surrounding areas of the Yellow Sea and Bohai Sea

暴雨灾害
Compared with other sea areas in China, the interaction between the Yellow and Bohai Sea surrounded by land on three sides and the mid latitude atmosphere has its uniqueness, and it is necessary to conduct research on the impact of air-sea coupled model ...
Lili LIU, Yinghua LI, Xuelian WANG, Yi LIN, Qiru DONG, Xiaobin QIU   +5 more
doaj   +1 more source

Development and Trajectory of Hurricane Eta—Case Study Using the WRF Model with Dynamic Update of the Sea Surface Temperature (SST) [PDF]

, 2022
Gretell Sosa-Martínez, Maibys Sierra Lorenzo, Osniel Armas-Forteza   +2 more
openalex   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

TIME-SPACE SEA SURFACE TEMPERATURE VARIABILITY, IN THE CARIBEAN SEA

Ra Ximhai, 2017
Twenty-one years of infrared satellite images of the Caribbean Sea were used from January 1983 to December 2002 to describe the sea surface temperature variability.
Emilio Palacios-Hernández, Laura Carrillo, Salvador Iván Meza-Romero, David Ávalos-Cueva   +3 more
doaj  

Sea-surface temperature anomalies and hurricane prediction

Geofísica Internacional, 1976
Es sabido que la temperatura de la superficie del mar (Ts) es un parámetro importante que afecta la formación y el movimiento de los huracanes. El efecto de la temperatura de la superficie del mar puede ser expresado en términos de anomalías.
Sergio Serra C., Enrique Buendía C.
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source