Results 101 to 110 of about 439,158 (345)
Sea surface circulation in the Baltic Sea: decomposed components and pattern recognition
Scientific ReportsBy decomposing the total sea surface current into its geostrophic and ageostrophic components, we examined the contribution of each to the long-term variability of the total sea surface current.
Amirhossein Barzandeh +6 more
doaj +1 more source
Известия ТИНРО, 2017 Data of observations on drifting buoys in the western Okhotsk Sea are presented. Quasi-stochastic mode of the buoys drift under forcing of atmospheric cyclone is noted.
Igor I. Usoltsev +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Measurement and parameterisation of the air-sea CO2 flux in high winds
, 2011 During a three year occupation of Station Mike (66°N 2°E), the Norwegian Ocean Weather Ship Polarfront was equipped with a range of meteorological and seastate measuring instruments, including the autonomous air-sea flux system “AutoFlux” (Yelland et al.,
Prytherch, John
core
Numerical simulations of strong wind situations near the Mediteranean French Coast: comparison with FETCH data [PDF]
, 2003 A detailed analysis is made of some typical strong wind situations near the French Mediterranean coast. Special attention has been paid to the wind from the north-northwest in the Gulf of Lion, also called the mistral.
Pezzoli, Alessandro +4 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Measurements of sub-surface bubble populations and the modelling of air-sea gas flux
, 2010 Bubbles, formed by breaking waves, play an important role in the transfer of gases between the Earth’s oceans and atmosphere and have been shown to increase the flux of gases during periods of heightened sea state.
Coles, David Geoffrey Hallstaff
core
The circular wind wave facilities at the University of Heidelberg [PDF]
, 1995 At the University of Heidelberg circular wind/wave flumes are used to study small-scale air sea interaction processes under a wide range of conditions. The outer diameter of the large flume is 4m and the channel width is 30 cm.
Jähne, Bernd +3 more
core +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source