Optimizing intervertebral disc cell metabolic phenotyping with machine learning and artificial neural networks. [PDF]
Bahar ME, Maulidi RF, Ngo QN, Kim DR.
europepmc +1 more source
Abstract figure legend Photobiomodulation restores blood–brain barrier (BBB) integrity following hypoxic stress. A multicellular human BBB model comprising brain microvascular endothelial cells, astrocytes and pericytes was established in a transwell system and subjected to acute hypoxia.
Mirriam Domocos +4 more
wiley +1 more source
Hippocampal Bioenergetics and Metabolic Profiling Identifies Fatty Acid Oxidation as a Potential Therapeutic Target in Traumatic Brain Injury. [PDF]
Zhou D +17 more
europepmc +1 more source
HIF2A as a prognostic and clinical therapeutic target in ovarian clear cell carcinoma
What's new? Ovarian clear cell carcinoma is highly associated with hypoxia. Hypoxia‐inducible factor 2A (HIF2A) is a key regulator of hypoxic responses, but its role in ovarian clear cell carcinoma remains unclear. This study demonstrated the unfavorable prognostic significance of HIF2A expression in ovarian clear cell carcinoma.
Mengxin Jiang +15 more
wiley +1 more source
Characterization of a <i>UQCRC1</i> variant in a patient with progressive weakness, pain and sleep issues reveals a functional mitochondrial defect restored by mitochondrial transplantation. [PDF]
Piroli GG +9 more
europepmc +1 more source
ABSTRACT Background Patients with end‐stage liver disease (ESLD) often present with sarcopenia, defined as loss of skeletal muscle mass and quality, which is associated with reduced quality of life and increased mortality. However, the molecular mechanisms driving sarcopenia in ESLD are not fully understood and there are currently no therapeutic ...
Thomas Nicholson +16 more
wiley +1 more source
Reversible Metabolic and Liver Disease in Complex III Deficiency: Novel Variants Expand the Reported <i>UQCRC2</i>-Associated Phenotype. [PDF]
Preston G +8 more
europepmc +1 more source
Minor epic: Notes toward a different “Anthropoetry”
Abstract Anthropologists have often turned to poetry as a means of accessing emotional registers of which conventional academic prose is unable to avail. In doing so, they have tacitly conflated poetry with lyric poetry, today probably the most widely practiced poetic genre, associated in particular with the expression of inner feelings and subjectival
Stuart McLean
wiley +1 more source
Microvessel and mitochondria changes in a mouse model of Alzheimer’s disease [PDF]
Hasselholt Stine +6 more
doaj +1 more source
Sex-dependent differences in bioenergetics of young mouse brain microvasculature: implications for oxygen-glucose deprivation and reoxygenation injury. [PDF]
Sure VN +11 more
europepmc +1 more source

