Results 211 to 220 of about 43,600 (294)

Trem1 regulates neutrophil metabolism and recruitment in lung ischemia-reperfusion injury. [PDF]

Redox Biol
Yang F, Tong S, Wan J, Li Y, Gao J, Sun Y, Sun X, Fu H, Luo W, Xu J, Zhou T, Babou S, Wu J, Zhang G, Chen C, Wang S.   +15 more
europepmc   +1 more source

YTHDF3 Mediates the Occurrence and Development of Breast Cancer by Regulating Glycolysis Through the mTOR–HIF1α–LHDA Axis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Breast cancer, a malignant tumour that frightens women, ruthlessly claims the lives of tens of thousands of women around the world every year. However, the mechanism by which YTHDF3 regulates the occurrence and development of breast cancer is still imperfect.
ZiQian Liu, TengFei Jiang, Peng Li, Ke Dong, XiMei Wang, ChenChen Geng, XiaoDong Zhang, Dan Zuo, GuangHui Zhao   +8 more
wiley   +1 more source

Modulating metabolic signatures to mitigate cabozantinib resistance in FLT3-ITD acute myeloid leukemia cell models. [PDF]

Cell Death Discov
Fu YH, Ng KM, Tseng CY, Huang AC, Tu CH, Chen WC, Lang PC, Chien HF, Lin LI.   +8 more
europepmc   +1 more source

Albumin Restores Endothelial Cell Mitochondrial Morphology in Patients With Decompensated Cirrhosis

Liver International, Volume 46, Issue 5, May 2026.
ABSTRACT Background & Aims Endothelial cell (EC) activation is a critical driver of disease progression in cirrhosis, contributing to acute decompensation (AD) and acute‐on‐chronic liver failure (ACLF). Although human albumin administration improves EC function in cirrhotic patients with hypoalbuminemia, its direct effects on ECs remain unclear.
Susan E. Fischer, Rudmer J. Postma, Roel Bijkerk, Annarein J. C. Kerbert, Anton Jan van Zonneveld, Minneke J. Coenraad   +5 more
wiley   +1 more source

Optimization and Application of Seahorse Glycolytic Stress Test in Mouse Corneal Tissues: Revealing Metabolic Profiles in Injury Models. [PDF]

Invest Ophthalmol Vis Sci
Yan X, Huang Y, Yang S, Chen G, Lin J, Guan Y, Zhu J, Chen X, Li X.   +8 more
europepmc   +1 more source

Salvia miltiorrhiza‐Derived Vesicle‐Like Nanoparticles Functionalised Hydrogel With Excellent Ability of Oxidative Stress Modulation and Anti‐Cardiomyocyte Apoptosis for Sepsis‐Induced Myocardial Injury

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3391-3406, May 2026.
ABSTRACT In the process of myocardial cell structural and functional damage caused by various factors, current therapeutic strategies primarily focus on restoring myocardial blood supply, often neglecting the inherent complex microenvironment triggered by elevated reactive oxygen species (ROS) levels during myocardial injury.
Zhichao Liu, Shixiang Chen, Baomin Dou, Zhen Shen, Hao Liu, Xizhen Wang, Liyue Zhu, Yue Qiu, Zhongxi Lyu, Te Ba, Kuicheng Li, Jinhong Chen, Ningcen Li   +12 more
wiley   +1 more source

Protocol to assess changes in mitochondrial respiration in living cultured cells infected with flaviviruses. [PDF]

STAR Protoc
Barragan Torres VA, Chatel-Chaix L.
europepmc   +1 more source

Obesity Disrupts H3K4me3‐Mediated Lactate Accumulation and Efferocytosis in Hypoxic Macrophages

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
Obesity disrupts macrophage adaptation to hypoxic microenvironments. In lean conditions, hypoxia induces H3K4me3‐dependent transcriptional programs that promote lactate accumulation, histone lactylation, and efficient efferocytosis. Diet‐induced obesity impairs this epigenetic–metabolic response, resulting in reduced lactate accumulation, defective ...
Kentaro Takahashi, Julia Drolet, Jinghua Liu, Jasmine R. Jackson, Madison Babcock, Muthusamy Thiruppathi, Milie Fang, Tyler Paul, Gayathri Ganesh, Yuri Fukasawa, Yoshikiyo Akasaka, Giamila Fantuzzi, Elizaveta V. Benevolenskaya, Timothy J. Koh, Norifumi Urao   +14 more
wiley   +1 more source

Contrasting Effects of Chronic Glucokinase Activation and Inhibition on Pancreatic Beta‐Cell Function

The FASEB Journal, Volume 40, Issue 7, 15 April 2026.
In the non‐diabetic beta‐cell (top left) activation of glucokinase (bottom left) leads to inhibition of mitochondrial metabolism and thereby impairs insulin secretion. The effect is similar to that of chronic hyperglycaemia as seen in the diabetic beta‐cell (top right).
Matthew Lloyd, Natascia Vedovato, Samuel J. Mullan, Alice Elphick, Aerin J. Dumenil, Chantal Rufer, Alexandra C. Title, Burcak Yesildag, Elizabeth Haythorne, Frances M. Ashcroft   +9 more
wiley   +1 more source

Mutant TDP-43 drives impairments in axonal transport and glycolysis in a mouse stem-cell-derived motor neuron model of amyotrophic lateral sclerosis (ALS). [PDF]

Cell Death Dis
Carroll E, Scaber J, Pasniceanu IS, Dafinca R, Gordon D, Candalija A, Talbot K.   +6 more
europepmc   +1 more source