Results 101 to 110 of about 4,985 (284)

A Viscous DES‐AAV‐Foxo1 Delivery System With High Transfection Efficiency for the Treatment of Corneal Endothelial Dysfunction by Restoring Mitochondria‐ER Contacts

open access: yesAdvanced Science, EarlyView.
High glucose triggers corneal endothelial dysfunction by impairing FOXO1‐mediated ITPR1 transcription, leading to disrupted mitochondria‐associated membrane (MAM) integrity and defective ER‐to‐mitochondria Ca2+ transfer. This study develops an innovative viscous DES‐AAV‐Foxo1 delivery system with enhanced transfection efficiency. This non‐invasive gene
Hongran Zhao   +10 more
wiley   +1 more source

The Official Student Newspaper of UAS [PDF]

open access: yes, 2015
Health Corner / Study Abroad -- Student Gov. Update / The Game is On -- Don't be S.A.D.

core  

Ontogenetic changes and sexual dimorphism in the cranium and mandible of the Atlantic walrus (Odobenus rosmarus rosmarus L.)

open access: yesThe Anatomical Record, EarlyView.
Abstract Walruses have been an important subsistence and cultural resource for humans and have been exploited for millennia across their distribution. This exploitation has contributed to severe declines in several populations and local extirpations.
Katrien Dierickx   +6 more
wiley   +1 more source

Seahorses [PDF]

open access: yesNeurology, 2016
openaire   +2 more sources

Broadening the semiaquatic scene: Quantification of long bone microanatomy across pinnipeds

open access: yesThe Anatomical Record, EarlyView.
Abstract Investigations of bone microanatomy are commonly used to explore lifestyle strategies in vertebrates. While distinct microanatomical limb bone features have been established for exclusively aquatic and terrestrial lifestyles, identifying clear patterns for the semiaquatic lifestyle remains more challenging.
Apolline Alfsen   +10 more
wiley   +1 more source

Patterns of spinal motion, kinematic spaces and the land‐to‐sea transition in carnivorans

open access: yesThe Anatomical Record, EarlyView.
Using 3D reconstructions, we quantify intervertebral joint mobility to investigate how cervical, thoracic, and lumbar vertebral regions evolved distinct kinematic roles in pinnipeds. The findings reveal lineage‐specific adaptations for swimming and highlight the functional significance of vertebral joint flexibility in ecological transitions.
Juan Miguel Esteban   +3 more
wiley   +1 more source

Effects of background color and aeration on survival, growth performance, skin color change rate, and standard metabolic rate of low quality juvenile pot-bellied seahorses (Hippocampus abdominalis)

open access: yesAquaculture Reports
Physical environmental conditions commonly affect the survival and growth performance of cultured seahorses. In addition, due to the differences of broodstock seahorses in quality or physical status (e.g.
Fengyuan Shen   +3 more
doaj   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

open access: yesArthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu   +12 more
wiley   +1 more source

The hypoxia adaptation strategy of the big-belly seahorses (Hippocampus abdominalis) with tuft gills

open access: yesAquaculture Reports
Hypoxia tolerance is a critical trait in fish breeding, however, the mechanisms underlying hypoxia regulation in the tuft gills of seahorses remain unclear.
Long-Wu Jia   +8 more
doaj   +1 more source

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