Results 111 to 120 of about 32,394 (293)
TwinPort: 5G drone-assisted data collection with digital twin for smart seaports. [PDF]
Sci Rep, 2023 Yigit Y +6 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Full steam ahead for Texas ports [PDF]
Trade ; North American Free Trade Agreement ; Petroleum industry and ...
José Joaquín López, Keith R. Phillips
core
Vikalpa: The Journal for Decision Makers, 1999 The main objective of port management is to reduce the ship turnaround time by optimally utilizing the port resources. Reduced turnaround time encourages trade and improves the competitiveness of the port to provide efficient and effective services at low cost. The management of Bharat Seaports Authority is wondering how to achieve this objective.
openaire +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Assessing the Port Footprint on Coastal Flood and Erosion Risks
Earth's FuturePorts are often perceived as sources of disruption to coastal environments, contributing to sediment imbalance, shoreline erosion and ecosystem service loss.
Moises Alvarez‐Cuesta +2 more
doaj +1 more source
Application of a fuzzy multi-criteria decision framework for safety-critical maritime infrastructure evaluation. [PDF]
Heliyon, 2023 Ighravwe DE, Mashao D.
europepmc +1 more source
Productivity Drivers in Japanese Seaports [PDF]
This paper analyses efficiency drivers of a representative sample of Japanese seaports by means of the two-stage procedure proposed by Simar and Wilson (2007).
Carlos Pestana Barros, Shunsuke Managi
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source