Results 31 to 40 of about 411,337 (293)
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Searching for Suicide Information on Web Search Engines in Chinese
Journal of Medical Sciences, 2017 Introduction: Recently, suicide prevention has been an important public health issue. However, with the growing access to information in cyberspace, the harmful information is easily accessible online.
Yen-Feng Lee +3 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Children's search engines on the Internet: an analytical study
Cybrarians JournalThe study focused on children's search engines with the main objective of cataloging the available children's search engines on the Internet and evaluating their strengths and weaknesses. A survey and analytical method were employed to achieve this goal.
Mohamed Al-Farjani
doaj +1 more source
Iranian Journal of Information Processing & Management, 2022 The aim of this study was to investigate the image retrieval from selected search engines according to the written and semantic features of Persian language and determine their relevance using recall and precision formulas and to identify the most ...
Yaghub Norouzi +2 more
doaj
AIB Studi, 2018 Il contributo propone una riflessione sul concetto di neutralità sia in riferimento a Internet e ai motori di ricerca, sia alle biblioteche. Nella prima parte, attraverso la presentazione di esempi e il rimando ad alcuni studi sul tema, l’autrice sfata ...
Karen Coyle
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
pp-Blast: a "pseudo-parallel" Blast
Brazilian Journal of Medical and Biological Research, 2003 We have developed a software called pp-Blast that uses the publicly available Blast package and PVM (parallel virtual machine) to partition a multi-sequence query across a set of nodes with replicated or shared databases.
E.C. Osório +4 more
doaj +1 more source
Interactive Search on the Web: The Story So Far
Information, 2022 Search on the web, specifically fetching of the relevant content, has been paid attention to since the advent of the web and particularly in recent years due to the tremendous growth in the volume of data and web pages.
Sareh Aghaei +5 more
doaj +1 more source
Searching the intranet: Corporate users and their queries [PDF]
, 2005 By examining the log files from a corporate intranet search engine, we have analysed the actual web searching behaviour of real users in a real business environment.
Stenmark, Dick
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