Results 51 to 60 of about 411,337 (293)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Eye-Tracking Studies of Web Search Engines: A Systematic Literature Review

open access: yesInformation, 2020
This paper analyzes peer-reviewed empirical eye-tracking studies of behavior in web search engines. A framework is created to examine the effectiveness of eye-tracking by drawing on the results of, and discussions concerning previous experiments.
Artur Strzelecki
doaj   +1 more source

A Survey on Blockchain-Based Search Engines

open access: yesApplied Sciences, 2021
With the increasing growth of different types of data, search engines have become an essential tool on the Internet. Every day, billions of queries are run through few search engines with several privacy violations and monopoly problems.
Esmaeel Rezaee   +2 more
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Special Intelligent Search Engine

open access: yesIranian Journal of Information Processing & Management, 2011
In this paper Special Intelligent Search Engine (SISE) design has been introduced. Also System architecture and methods of this component of its intelligent search engine and features have been described.
Reza Sarabadani, Hossein Shirazi
doaj  

التشتت النوعی لمحرکات البحث ومدى الوعی بها والإفادة منها [PDF]

open access: yesالمجلة الدولية لعلوم المكتبات والمعلومات, 2016
From the public perspective to organize the digital informationenvironment, we find that the search engines are the biggest tools that regulatethe online environment and allows sources to beneficiaries, The volume ofinformation available on the Internet ...
د. عزة فاروق الجوهرى
doaj   +1 more source

Search Engine Use 2012 [PDF]

open access: yes, 2012
Presents survey findings about Americans' use of search engines and how they view their own Internet search abilities, search engine performance, and the collection of user information to personalize search results or target ...
Joanna Brenner   +2 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Qualitative ranking of Persian and non-Persian search engines in information retrieval of Islamic subjects [PDF]

open access: yesکتابداری و اطلاع‌رسانی, 2016
Purpose: The purpose of this study was to determine the quality of the content of web pages in the Islamic domain retrieved by Persian and non Persian search engines. Methodology:This was an applied research carried out through descriptive survey. A self-
Naeimeh Morvarid   +2 more
doaj  

OPTIMIZING KEYWORD SEARCH FOR SEARCH ENGINES USING BLOCKCHAIN TECHNOLOGY [PDF]

open access: yesProceedings on Engineering Sciences
The traditional SEO landscape, reliant on algorithmic changes and privacy concerns, demands new solutions. This research explores the integration of blockchain technology into SEO to boost website visibility without compromising user privacy.
Bharti Aggarwal   +2 more
doaj   +1 more source

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