Results 61 to 70 of about 411,337 (293)

Sometimes the Internet reads the question wrong: children’s search strategies & difficulties [PDF]

open access: yes, 2014
When children search for information on a given topic, how do they go about searching for and retrieving information? What can their information seeking strategies tell us about the development of search interfaces for children's digital libraries ...
Cunningham, Sally Jo   +2 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

What Users See – Structures in Search Engine Results Pages [PDF]

open access: yes, 2009
This paper investigates the composition of search engine results pages. We define what elements the most popular web search engines use on their results pages (e.g., organic results, advertisements, shortcuts) and to which degree they are used for ...
Höchstötter, Nadine, Lewandowski, Dirk
core  

A low-power network search engine based on statistical partitioning [PDF]

open access: yes, 2004
Network search engines based on Ternary CAMs are widely used in routers. However, due to parallel search nature of TCAMs power consumption becomes a critical issue.
Basci, F, Kocak, T
core   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Extending Yioop! With Geographical Location Local Search [PDF]

open access: yes, 2012
It is often useful when doing an internet search to get results based on our current location. For example, we might want such results when we search on restaurants, car service center, or hospitals. Current open source search engines like those based on
Sinha, Vijaya
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Search Engine Users [PDF]

open access: yes, 2005
Presents findings from a survey conducted in May and June 2004. Looks at confidence in search ability; satisfaction with results; overall trust of search engines; and demographic differences among ...
Deborah Fallows
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

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